DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Prdm13 and kmg

DIOPT Version :9

Sequence 1:NP_648032.1 Gene:Prdm13 / 38713 FlyBaseID:FBgn0035687 Length:465 Species:Drosophila melanogaster
Sequence 2:NP_609604.1 Gene:kmg / 34706 FlyBaseID:FBgn0032473 Length:747 Species:Drosophila melanogaster


Alignment Length:560 Identity:89/560 - (15%)
Similarity:146/560 - (26%) Gaps:228/560 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 LEQKRSASLIFRIEQ--LLPSTSITPTSMTTSSTETTL------TATTSTASPAKRMRMS----- 61
            |||.::.:.:|.:..  .:.:.|..|..:...:.|.:|      ........|..::|.:     
  Fly    57 LEQYKANNFMFPLSMAGFVSADSAPPGDLAKENMENSLPDGNPCNNNNDDELPQCKIRRNYSCNQ 121

  Fly    62 ------NPRPG--------------------VYASQYTPKDTCSMAI------PTSALLGSTVMP 94
                  |||..                    :|||::..|....|.:      ...|:.||...|
  Fly   122 CAFFTQNPRSHLSHLRDVHGERIVINECKLCLYASRHFQKLVRHMKMVHGCSDDGGAVQGSGAQP 186

  Fly    95 T--------------------DGSRSHC-QLSNGELIVSGSLLRQIKL---SEDVYSFNAIFELH 135
            .                    .|:...| .||...:|.:|..|.|:|:   .:::....::...:
  Fly   187 RGKRNLSREVRKRRLEESIEGQGATGQCLDLSVLRMIQNGPPLEQLKVELQQQEMQLLASVQAYN 251

  Fly   136 GGQVRVRLVRDVAREDEIVAWFGEELVLLMGIPFLTPLN-------------------------- 174
            ..|..::|.:.|...|.|.:         |...|.|.|.                          
  Fly   252 RQQEMLQLQQIVESHDNIFS---------MAYEFQTKLMPPKQAESLKLEQQNSSSDSEETAKSP 307

  Fly   175 -------IQGNSRYMCHLCHLT-------------------------FETP-----------HPL 196
                   :.|..::.|..|..:                         |.||           |..
  Fly   308 SPDTRELVSGKEQFQCQKCSYSTPIRARFKKHVKYHSMPLIKCSSCDFHTPYKWNLDRHTKNHGA 372

  Fly   197 KIHLALGCGRSAMDILWMRLHYALKAAARSHTETQHSPIPA----------------TSSTSSAS 245
            ..|....|...:.||         |.:...|....|.|:|.                ..|:.|..
  Fly   373 NGHFKCSCCDFSTDI---------KQSLTIHESNHHVPMPVHQMGNRSRDEAEDLVDQQSSGSRK 428

  Fly   246 P--------THSPPPQMPPRFSAF------RPIAALTQSLPMVPVTT------------------ 278
            |        |.:....:.||.|..      :.:....|.:..:.|.|                  
  Fly   429 PETFKNGGATVASTESLLPRTSGIVCSHCQKRVGNAMQLINHLQVCTLALHNTTQLQASINAEVD 493

  Fly   279 --------AATPLSY-----LPSMSMATAPLSTNPMNAAAQIEAIVSNMGASKQGHLCIYCGKVY 330
                    |.|.|||     .|.....|..|...|           .::...|:...|.:|....
  Fly   494 LHDEDFPNAPTDLSYCGVETAPGYGEVTEVLPEEP-----------EDLAPLKKVFKCPHCSFWA 547

  Fly   331 SRKYGLKIHIRTHTGFKPLKCKFCLRPFGDPSNLNKHVRL 370
            :......:||..|...||.:|..|........::.||:||
  Fly   548 ATASRFHVHIVGHLNRKPFECSLCAYRSNWRWDITKHIRL 587

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prdm13NP_648032.1 COG5048 280..>380 CDD:227381 22/96 (23%)
C2H2 Zn finger 323..343 CDD:275368 4/19 (21%)
zf-H2C2_2 336..358 CDD:290200 7/21 (33%)
C2H2 Zn finger 351..371 CDD:275368 6/20 (30%)
zf-C2H2 406..427 CDD:278523
C2H2 Zn finger 408..427 CDD:275368
kmgNP_609604.1 C2H2 Zn finger 540..560 CDD:275370 4/19 (21%)
C2H2 Zn finger 568..586 CDD:275370 4/17 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24403
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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