DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prdm13 and sens-2

DIOPT Version :9

Sequence 1:	NP_648032.1	Gene:	Prdm13 / 38713	FlyBaseID:	FBgn0035687	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001285692.1	Gene:	sens-2 / 33957	FlyBaseID:	FBgn0051632	Length:	746	Species:	Drosophila melanogaster

Alignment Length:	293	Identity:	64/293 - (21%)
Similarity:	100/293 - (34%)	Gaps:	95/293 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   176 QGNSRYMCHLCHLTFETPHPLKIHLALGCGRSAMDILWMRLHYALKAAARSHTETQHSPIPATSS 240
            |.:..|.|..|...|.|||.|::|.             .|.|:..|..|   .|..:.......|
  Fly   502 QFSDLYSCMKCEKMFSTPHGLEVHS-------------RRTHHGKKPYA---CELCNKTFGHEVS 550

  Fly   241 TSSASPTHSPP-----PQMPPRFSAFRPIAALTQSLPMVPVTTAATPLSYLPSMSMATAPLSTNP 300
            .|.....|:..     .|...||.                                .::.|||:.
  Fly   551 LSQHRAVHNVEKVFECKQCGKRFK--------------------------------RSSTLSTHL 583

  Fly   301 MNAAAQIEAIVSNMGASKQGHLCIYCGKVYSRKYGLKIHIRTHTGFKPLKCKFCLRPFGDPSNLN 365
            :            :.:..:.:.|.||||.:.:|..:|.|...|||.||.||:.|.:.|...|||.
  Fly   584 L------------IHSDTRPYPCNYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLI 636

  Fly   366 KHVRLHLQTHPSSSAGVADGGASGADMDGDVDIEGETDADYQCHVCHKSFPRRRDLQRHMETRHG 430
            .|.|.|....|                             :.|.:|||:|.|:.||:||.||:|.
  Fly   637 THSRKHTGYKP-----------------------------FSCKLCHKAFQRKVDLRRHKETQHT 672

  Fly   431 GHHSH-SHSESRSSSTSTSSTTTMTATVTTSTS 462
            ....| ...:..|::.:.:::..::|....:.:
  Fly   673 DLRVHLGKVDFMSAAAAAAASAELSAAAAAAAA 705

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prdm13	NP_648032.1	COG5048	280..>380	CDD:227381	27/99 (27%)
		C2H2 Zn finger	323..343	CDD:275368	8/19 (42%)
		zf-H2C2_2	336..358	CDD:290200	10/21 (48%)
		C2H2 Zn finger	351..371	CDD:275368	8/19 (42%)
		zf-C2H2	406..427	CDD:278523	10/20 (50%)
		C2H2 Zn finger	408..427	CDD:275368	10/18 (56%)
sens-2	NP_001285692.1	COG5048	<504..672	CDD:227381	59/256 (23%)
		C2H2 Zn finger	509..530	CDD:275368	9/33 (27%)
		zf-H2C2_2	522..545	CDD:290200	7/38 (18%)
		C2H2 Zn finger	538..558	CDD:275368	3/19 (16%)
		zf-H2C2_2	550..575	CDD:290200	6/56 (11%)
		C2H2 Zn finger	566..586	CDD:275368	6/63 (10%)
		zf-H2C2_2	579..603	CDD:290200	8/35 (23%)
		C2H2 Zn finger	594..614	CDD:275368	8/19 (42%)
		zf-H2C2_2	606..631	CDD:290200	11/24 (46%)
		C2H2 Zn finger	622..642	CDD:275368	8/19 (42%)
		zf-H2C2_2	634..657	CDD:290200	10/51 (20%)
		C2H2 Zn finger	650..677	CDD:275368	13/26 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447764
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930