DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prdm13 and Zfp407

DIOPT Version :9

Sequence 1:	NP_648032.1	Gene:	Prdm13 / 38713	FlyBaseID:	FBgn0035687	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_008770443.2	Gene:	Zfp407 / 307213	RGDID:	1310645	Length:	2255	Species:	Rattus norvegicus

Alignment Length:	407	Identity:	78/407 - (19%)
Similarity:	129/407 - (31%)	Gaps:	161/407 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 RSHCQLSNGELIVSGSLLRQIKLSED--------------------------VYSFNAIFELHGG 137
            :::..|.:.|::::.....::.|.||                          :|||        |
  Rat  1288 QANSNLESKEILMNSQHEPEVILEEDAPASIGTAENNDAYETIISIDDKGQTMYSF--------G 1344

  Fly   138 QVRVRLVRDVAREDEIVAWFGEELVLLMGIPFLTPL----------NIQGNS-----RYMCHLCH 187
            :....::|....:.|:|....|.|::..|.....||          .::|:|     |..|..|.
  Rat  1345 RFDSSIIRIKTEDGELVEQPEEGLMVTGGKVSELPLKDCAQGLKKKKVEGSSFGESTRIRCDDCG 1409

  Fly   188 LTFETPHPLKIHLA------------LGCGRSAMDILWMRLHYALKAAARSHTETQHSPIPATSS 240
            ...:....|.:|:|            |.||:|.  .....||..|  |:..|...:.:.:
  Rat  1410 FLADGLSGLNVHIAMKHPTKEKHFHCLLCGKSF--YTESNLHQHL--ASAGHMRNEQASV----- 1465

  Fly   241 TSSASPTHSPPPQMPPRFSAFRPIAALTQSLPMVPVTTAATPLSYLPSMSMATAPLSTNP---MN 302
                       .::|...:.|:.:                          ..|.|..:..   ::
  Rat  1466 -----------EELPEGGATFKCV--------------------------KCTEPFDSEQNLFLH 1493

  Fly   303 AAAQIEAIVSNMG--------------ASKQGHLCIYCGKV--YSRKYGLKIHIRTHTGFKPLKC 351
            ...|.|.::..:.              ...||::|.||||:  .|.......|||||||.||.||
  Rat  1494 IKGQHEELLREVNKYIVEDTEQINREREENQGNVCKYCGKMCRSSNSMAFLAHIRTHTGSKPFKC 1558

  Fly   352 KFC---LRPFGDPSNLNKHVRLHLQTHPSSSAGVADGGASGADMDGDVDIEGETDADYQCHVCHK 413
            |.|   ....||..|   ||:.||...                             :|:||||..
  Rat  1559 KICHFATAQLGDARN---HVKRHLGMR-----------------------------EYKCHVCGV 1591

  Fly   414 SFPRRRDLQRHMETRHG 430
            :|..::.|..|:..:||
  Rat  1592 AFVMKKHLNTHLLGKHG 1608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prdm13	NP_648032.1	COG5048	280..>380	CDD:227381	32/121 (26%)
		C2H2 Zn finger	323..343	CDD:275368	9/21 (43%)
		zf-H2C2_2	336..358	CDD:290200	13/24 (54%)
		C2H2 Zn finger	351..371	CDD:275368	8/22 (36%)
		zf-C2H2	406..427	CDD:278523	8/20 (40%)
		C2H2 Zn finger	408..427	CDD:275368	7/18 (39%)
Zfp407	XP_008770443.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24403
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100