DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prdm13 and Zfp407

DIOPT Version :9

Sequence 1:NP_648032.1 Gene:Prdm13 / 38713 FlyBaseID:FBgn0035687 Length:465 Species:Drosophila melanogaster
Sequence 2:NP_001028513.2 Gene:Zfp407 / 240476 MGIID:2685179 Length:2246 Species:Mus musculus


Alignment Length:499 Identity:95/499 - (19%)
Similarity:151/499 - (30%) Gaps:197/499 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 TTSSTETTLTATTSTASPA-----------KRMRMSNPRPGVYASQYTPKDTCS--MAIPTSALL 88
            |.......|.|....::|.           :::...:|.||.....::.:.|.|  |.||...| 
Mouse  1204 TAKKNRDVLDAVGDRSTPCEDEGGSVDDSEEKILDKSPCPGDPDGGHSAESTSSVVMKIPREQL- 1267

  Fly    89 GSTVMPTDG---SRSHCQ--------------LSNGELIVSGSLLRQIKLSED------------ 124
                 ..||   ::..|:              |.|.|::::.....::.|.||            
Mouse  1268 -----DLDGGGQNKVGCEQTSEDLKDVQANPILENKEILINSQEEAEVILEEDAPTSNGTADSND 1327

  Fly   125 --------------VYSFNAIFELHGGQVRVRLVRDVAREDEIVAWFGEELVLLMGIPFLTPL-- 173
                          :|||        |:....::|....:.|:|....|.|....|.....||  
Mouse  1328 VYETIISIDDKGQTMYSF--------GRFDSSIIRIKTEDGELVEQPEEGLTATGGRVSELPLKD 1384

  Fly   174 --------NIQGNS-----RYMCHLCHLTFETPHPLKIHLA------------LGCGRSAMDILW 213
                    .::|.|     |..|..|....:....|.:|:|            |.||:|.  ...
Mouse  1385 CAQGLKKKKVEGGSFGESTRIRCDDCGFLADGLSGLNVHIAMKHPTKEKHFHCLLCGKSF--YTE 1447

  Fly   214 MRLHYALKAAARSHTETQHSPIPATSSTSSASPTHSPPPQMPPRFSAFRPIAALTQSLPMVPVTT 278
            ..||..|  |:..|...:.:.:                .::|...:.|:.:              
Mouse  1448 SNLHQHL--ASAGHMRNEQASV----------------EELPEGGATFKCV-------------- 1480

  Fly   279 AATPLSYLPSMSMATAPLSTNP---MNAAAQIEAIVSNMG--------------ASKQGHLCIYC 326
                        ..|.|..:..   ::...|.|.::..:.              ...||::|.||
Mouse  1481 ------------KCTEPFDSEQNLFLHIKGQHEELLREVNKYIVEDTEQINREREENQGNVCKYC 1533

  Fly   327 GKV--YSRKYGLKIHIRTHTGFKPLKCKFC---LRPFGDPSNLNKHVRLHLQTHPSSSAGVADGG 386
            ||:  .|.......|||||||.||.|||.|   ....||..|   ||:.||...           
Mouse  1534 GKMCRSSNSMAFLAHIRTHTGSKPFKCKICHFATAQLGDARN---HVKRHLGMR----------- 1584

  Fly   387 ASGADMDGDVDIEGETDADYQCHVCHKSFPRRRDLQRHMETRHG 430
                              :|:||||..:|..::.|..|:..:||
Mouse  1585 ------------------EYKCHVCGVAFVMKKHLNTHLLGKHG 1610

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prdm13NP_648032.1 COG5048 280..>380 CDD:227381 32/121 (26%)
C2H2 Zn finger 323..343 CDD:275368 9/21 (43%)
zf-H2C2_2 336..358 CDD:290200 13/24 (54%)
C2H2 Zn finger 351..371 CDD:275368 8/22 (36%)
zf-C2H2 406..427 CDD:278523 8/20 (40%)
C2H2 Zn finger 408..427 CDD:275368 7/18 (39%)
Zfp407NP_001028513.2 C2H2 Zn finger 180..200 CDD:275368
C2H2 Zn finger 209..230 CDD:275368
C2H2 Zn finger 524..552 CDD:275371
C2H2 Zn finger 553..575 CDD:275371
C2H2 Zn finger 1407..1436 CDD:275371 5/28 (18%)
C2H2 Zn finger 1437..1459 CDD:275371 8/25 (32%)
C2H2 Zn finger 1479..1500 CDD:275371 2/46 (4%)
C2H2 Zn finger 1530..1552 CDD:275368 9/21 (43%)
zf-H2C2_2 1548..1569 CDD:290200 13/20 (65%)
C2H2 Zn finger 1560..1580 CDD:275368 8/22 (36%)
C2H2 Zn finger 1588..1608 CDD:275368 7/19 (37%)
COG5048 <1618..1737 CDD:227381
C2H2 Zn finger 1621..1641 CDD:275368
zf-H2C2_2 1633..1660 CDD:290200
C2H2 Zn finger 1649..1671 CDD:275368
C2H2 Zn finger 1679..1699 CDD:275368
zf-H2C2_2 1691..1716 CDD:290200
COG5048 1703..>1758 CDD:227381
C2H2 Zn finger 1707..1727 CDD:275368
zf-H2C2_2 1719..1744 CDD:290200
C2H2 Zn finger 1735..1752 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24403
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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