DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prdm13 and ZNF513

DIOPT Version :9

Sequence 1:NP_648032.1 Gene:Prdm13 / 38713 FlyBaseID:FBgn0035687 Length:465 Species:Drosophila melanogaster
Sequence 2:NP_653232.3 Gene:ZNF513 / 130557 HGNCID:26498 Length:541 Species:Homo sapiens


Alignment Length:370 Identity:76/370 - (20%)
Similarity:106/370 - (28%) Gaps:145/370 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   166 GIPFLTPLNIQGNSRYMCHLCHLTFETPHPLKIHL-------ALGCGR---SAMDILWMRLHYAL 220
            |.|.|.|..:     |.|.||.........||.|:       ...|||   ::..::.:..|   
Human   140 GGPLLPPRLL-----YSCRLCTFVSHYSSHLKRHMQTHSGEKPFRCGRCPYASAQLVNLTRH--- 196

  Fly   221 KAAARSHT-----ETQHSPIPATS--STSSASPTHSPPPQMPPRFSAFRPIAALTQSLPMVPVTT 278
               .|:||     ...|.|...:|  :......||:.||..|.....||.........|......
Human   197 ---TRTHTGEKPYRCPHCPFACSSLGNLRRHQRTHAGPPTPPCPTCGFRCCTPRPARPPSPTEQE 258

  Fly   279 AATP-----LSYLPSMSMATAPLSTNPMNAAAQI------------------------------- 307
            .|.|     ...||.:|:...|...:.:....|:                               
Human   259 GAVPRRPEDALLLPDLSLHVPPGGASFLPDCGQLRGEGEGLCGTGSEPLPELLFPWTCRGCGQEL 323

  Fly   308 -EAIVSNMGASKQG------------------------------------HL------------- 322
             |...|.:||:..|                                    ||             
Human   324 EEGEGSRLGAAMCGRCMRGEAGGGASGGPQGPSDKGFACSLCPFATHYPNHLARHMKTHSGEKPF 388

  Fly   323 -CIYCGKVYSRKYGLKIHIRTHTGFKPLKCKFCLRPFGDPSNLNKHVRLHLQTHPSSSAGVADGG 386
             |..|....:....||.|.|.|||.||.||..|....|:.:||.:|.|:|               
Human   389 RCARCPYASAHLDNLKRHQRVHTGEKPYKCPLCPYACGNLANLKRHGRIH--------------- 438

  Fly   387 ASGADMDGDVDIEGETDADYQCHVCHKSFPRRRDLQRHMETRHGG 431
             ||             |..::|.:|:.|..:..:|:||| .||.|
Human   439 -SG-------------DKPFRCSLCNYSCNQSMNLKRHM-LRHTG 468

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prdm13NP_648032.1 COG5048 280..>380 CDD:227381 34/186 (18%)
C2H2 Zn finger 323..343 CDD:275368 6/19 (32%)
zf-H2C2_2 336..358 CDD:290200 12/21 (57%)
C2H2 Zn finger 351..371 CDD:275368 7/19 (37%)
zf-C2H2 406..427 CDD:278523 7/20 (35%)
C2H2 Zn finger 408..427 CDD:275368 7/18 (39%)
ZNF513NP_653232.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..118
C2H2 Zn finger 152..172 CDD:275368 6/19 (32%)
COG5048 176..>228 CDD:227381 10/57 (18%)
C2H2 Zn finger 180..200 CDD:275368 5/25 (20%)
zf-H2C2_2 192..217 CDD:316026 6/30 (20%)
C2H2 Zn finger 208..228 CDD:275368 3/19 (16%)
C2H2 Zn finger 362..382 CDD:275368 2/19 (11%)
COG5048 <372..>450 CDD:227381 26/106 (25%)
C2H2 Zn finger 390..410 CDD:275368 6/19 (32%)
COG5048 414..>487 CDD:227381 24/85 (28%)
C2H2 Zn finger 418..438 CDD:275368 7/19 (37%)
C2H2 Zn finger 446..466 CDD:275368 7/20 (35%)
C2H2 Zn finger 474..493 CDD:275368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 492..541
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24403
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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