DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZKSCAN4 and CG6813

DIOPT Version :9

Sequence 1:NP_061983.2 Gene:ZKSCAN4 / 387032 HGNCID:13854 Length:545 Species:Homo sapiens
Sequence 2:NP_001163590.1 Gene:CG6813 / 41396 FlyBaseID:FBgn0037923 Length:294 Species:Drosophila melanogaster


Alignment Length:228 Identity:69/228 - (30%)
Similarity:99/228 - (43%) Gaps:39/228 - (17%)


- Green bases have known domain annotations that are detailed below.


Human   234 WTQLDSSQVNLYRDEKQENHSSLVSLGGEIQTKSRDLPPVKKLPEKEHGKICHLREDIAQIPTHA 298
            :..:|.:|:....||      |::            .|.||.||.....|:        ..||  
  Fly    91 YEDIDDNQIESELDE------SIL------------CPEVKDLPMPSAEKV--------SAPT-- 127

Human   299 EAGEQEGRLQRKQKNAIGSRRHYCHECGKSFAQSSGLTKHRRIHTGEKPYECE--DCGKTFIGSS 361
                   .|..::....|:..:.|.:||:.....|...:|...|||.|.:.|.  :|.::|....
  Fly   128 -------SLNHQKSIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRK 185

Human   362 ALVIHQRVHTGEKPYECEECGKVFSHSSNLIKHQRTHTGEKPYECDDCGKTFSQSCSLLEHHKIH 426
            .|..|.|:||||:||.|..|.:.||.|....:|.|.|..|:.||||.|.|:|..|..|.:|..||
  Fly   186 ELTSHTRIHTGEQPYVCVYCPRRFSSSGARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIH 250

Human   427 TGEKPYQCNMCGKAFRRNSHLLRH--QRIHGDK 457
            ...:.:.|.:|.|.|:|.|||:.|  ..||..|
  Fly   251 VDARNHYCYVCQKHFKRISHLMTHLSSNIHKRK 283

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZKSCAN4NP_061983.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..22
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 34..55
SCAN 49..160 CDD:128708
KRAB 221..281 CDD:214630 10/46 (22%)
zf-C2H2 320..342 CDD:306579 5/21 (24%)
C2H2 Zn finger 322..342 CDD:275368 5/19 (26%)
zf-H2C2_2 335..357 CDD:316026 7/23 (30%)
C2H2 Zn finger 350..370 CDD:275368 6/21 (29%)
COG5048 <374..544 CDD:227381 35/86 (41%)
C2H2 Zn finger 378..398 CDD:275368 7/19 (37%)
C2H2 Zn finger 406..426 CDD:275368 8/19 (42%)
C2H2 Zn finger 434..454 CDD:275368 9/21 (43%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 455..480 1/3 (33%)
C2H2 Zn finger 489..509 CDD:275368
C2H2 Zn finger 517..537 CDD:275368
CG6813NP_001163590.1 zf-AD 6..76 CDD:285071
C2H2 Zn finger 144..164 CDD:275368 5/19 (26%)
C2H2 Zn finger 172..194 CDD:275368 6/21 (29%)
zf-H2C2_2 186..211 CDD:290200 12/24 (50%)
UFD2 <256..>294 CDD:227443 12/28 (43%)
C2H2 Zn finger 258..280 CDD:275368 9/21 (43%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.960

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