Protein Alignment ZKSCAN4 and crol

DIOPT Version :9

• Sequence 1: NP_061983.2
• Gene: ZKSCAN4 / 387032
• HGNCID: 13854
• Length: 545
• Species: Homo sapiens
• Sequence 2: NP_001245993.1
• Gene: crol / 34592
• FlyBaseID: FBgn0020309
• Length: 962
• Species: Drosophila melanogaster
• Alignment Length: 279
• Identity: 102/279 - (36%)
• Similarity: 139/279 - (49%)
• Gaps: 25/279 - (8%)

Human   274 KKLPEKEHGKICHLREDIAQIPTHAE-AGEQEGRLQRKQKNAI---GSRRHYCHECGKSFAQSSG 334
            ||...||| ...|:|....:.|...| .|:...|.:....:.:   |...|.|..|.|:|.:...
  Fly   396 KKYTRKEH-LANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEH 459

Human   335 LTKHRRIHTGEKPYECEDCGKTFIGSSALVIHQRVHTGEKPYECEECGKVFSHSSNLIKHQRTHT 399
            |..|.|.||||.|:.|..|.|||.....||.|.|.||||.|::|..|.|.|:...:::.|.|.||
  Fly   460 LLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHT 524

Human   400 GEKPYECDDCGKTFSQSCSLLEHHKIHTGEKPYQCNMCGKAFRRNSHLLRHQRIH-GD------- 456
            ||.|::|..|.|||::...|..|.:.|||:.|::|:.|.|.|.|..||..|.|:| ||
  Fly   525 GESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEY 589

Human   457 --KNVQNPEHGESWESQGRTESQWENTEAPVSYKCNECERSFTRNRSLIEH-QKIHTGEKPYQCD 518
              |.....||..:...|..:::         .:.||.|.:.|||...||.| .:.|||::|:.|:
  Fly   590 CQKTFTRKEHLNNHMRQHSSDN---------PHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCE 645

Human   519 TCGKGFTRTSYLVQHQRSH 537
            ||||.|.....|:.|||||
  Fly   646 TCGKSFPLKGNLLFHQRSH 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZKSCAN4	NP_061983.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..55
		SCAN	49..160	CDD:128708
		KRAB	221..281	CDD:214630	3/6 (50%)
		zf-C2H2	320..342	CDD:306579	8/21 (38%)
		C2H2 Zn finger	322..342	CDD:275368	7/19 (37%)
		zf-H2C2_2	335..357	CDD:316026	11/21 (52%)
		C2H2 Zn finger	350..370	CDD:275368	9/19 (47%)
		COG5048	<374..544	CDD:227381	64/175 (37%)
		C2H2 Zn finger	378..398	CDD:275368	6/19 (32%)
		C2H2 Zn finger	406..426	CDD:275368	7/19 (37%)
		C2H2 Zn finger	434..454	CDD:275368	9/19 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	455..480		6/33 (18%)
		C2H2 Zn finger	489..509	CDD:275368	9/20 (45%)
		C2H2 Zn finger	517..537	CDD:275368	10/19 (53%)
crol	NP_001245993.1	C2H2 Zn finger	223..243	CDD:275368
		C2H2 Zn finger	251..271	CDD:275368
		C2H2 Zn finger	279..299	CDD:275368
		COG5048	300..723	CDD:227381	102/279 (37%)
		C2H2 Zn finger	307..327	CDD:275368
		C2H2 Zn finger	335..355	CDD:275368
		C2H2 Zn finger	363..383	CDD:275368
		C2H2 Zn finger	391..411	CDD:275368	7/15 (47%)
		C2H2 Zn finger	419..439	CDD:275368	3/19 (16%)
		C2H2 Zn finger	447..467	CDD:275368	7/19 (37%)
		C2H2 Zn finger	475..495	CDD:275368	9/19 (47%)
		C2H2 Zn finger	503..523	CDD:275368	6/19 (32%)
		C2H2 Zn finger	531..551	CDD:275368	7/19 (37%)
		C2H2 Zn finger	559..579	CDD:275368	9/19 (47%)
		C2H2 Zn finger	587..607	CDD:275368	3/19 (16%)
		C2H2 Zn finger	615..636	CDD:275368	9/20 (45%)
		C2H2 Zn finger	644..664	CDD:275368	10/19 (53%)
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	704..722	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010