DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZKSCAN4 and si:cabz01069022.1

DIOPT Version :9

Sequence 1:NP_061983.2 Gene:ZKSCAN4 / 387032 HGNCID:13854 Length:545 Species:Homo sapiens
Sequence 2:XP_017211315.1 Gene:si:cabz01069022.1 / 100332864 ZFINID:ZDB-GENE-161017-86 Length:313 Species:Danio rerio


Alignment Length:345 Identity:113/345 - (32%)
Similarity:147/345 - (42%) Gaps:97/345 - (28%)


- Green bases have known domain annotations that are detailed below.


Human   248 EKQENHSSLVSLGGEIQTKSRDLPPVKK--------------LPEKEHGKICHLREDIAQIPTHA 298
            |:...|..|..     ||   ||.|||:              |.||.|..:...:..|:|  |..
Zfish    14 EETFTHEDLAE-----QT---DLMPVKEEEIQDLNIIKVEIDLDEKHHEFMSGEKNSISQ--TEN 68

Human   299 EAGEQEGRLQRKQKNAIGSRRH-------------------YCHECGKSFAQSSGLTKHRRIHTG 344
            ...|:|.          ||..|                   .|.:|||||.:...|..|..||||
Zfish    69 TFSEEEA----------GSTFHSSHSSNFNLQTIHTAEKTFSCQQCGKSFNKKGNLKVHMTIHTG 123

Human   345 EKPYECEDCGKTFIGSSALVIHQRVHTGEKPYECEECGKVFSHSSNLIKHQRTHTGEKPYECDDC 409
            ||.:.|:.|||.|....:|.:|.|||||||.:.|::|||.||...|||.|...|..|..:.|..|
Zfish   124 EKNFSCQQCGKRFNQQGSLNVHMRVHTGEKLFTCQQCGKNFSQRGNLINHMVVHNSENTFTCQQC 188

Human   410 GKTFSQSCSLLEHHKIHTGEKPYQCNMCGKAFRRNSHLLRHQRIH-GDKNVQNPEHGESWESQGR 473
            ||:|::..:|..|.::||||||:.|..||.:|.:...:..|.|:| |.|                
Zfish   189 GKSFNRKGNLKVHMRVHTGEKPFTCQQCGISFAQKGGIDEHMRLHTGVK---------------- 237

Human   474 TESQWENTEAPVSYKCNECERSFTRNRSLIEHQKIHTGEKPYQCDTCGKGFTRTSYLVQHQRS-H 537
                        ::.|.||..||||..:|..|.:|||||.||.|..||..|...:.|.:|.|: |
Zfish   238 ------------TFICPECGVSFTRKGNLKVHMRIHTGENPYTCQQCGMSFILKATLKRHIRTQH 290

Human   538 V--------------GKKTL 543
            |              .||||
Zfish   291 VESGSPASTAERHSPNKKTL 310

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZKSCAN4NP_061983.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..22
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 34..55
SCAN 49..160 CDD:128708
KRAB 221..281 CDD:214630 13/46 (28%)
zf-C2H2 320..342 CDD:306579 9/40 (23%)
C2H2 Zn finger 322..342 CDD:275368 8/19 (42%)
zf-H2C2_2 335..357 CDD:316026 12/21 (57%)
C2H2 Zn finger 350..370 CDD:275368 8/19 (42%)
COG5048 <374..544 CDD:227381 64/186 (34%)
C2H2 Zn finger 378..398 CDD:275368 10/19 (53%)
C2H2 Zn finger 406..426 CDD:275368 7/19 (37%)
C2H2 Zn finger 434..454 CDD:275368 6/19 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 455..480 2/24 (8%)
C2H2 Zn finger 489..509 CDD:275368 9/19 (47%)
C2H2 Zn finger 517..537 CDD:275368 7/20 (35%)
si:cabz01069022.1XP_017211315.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 212 1.000 Inparanoid score I10838
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.960

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