DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ets65A and ets2

DIOPT Version :9

Sequence 1:	NP_001303373.1	Gene:	Ets65A / 38700	FlyBaseID:	FBgn0005658	Length:	728	Species:	Drosophila melanogaster
Sequence 2:	NP_001018874.1	Gene:	ets2 / 326672	ZFINID:	ZDB-GENE-050522-552	Length:	439	Species:	Danio rerio

Alignment Length:	290	Identity:	103/290 - (35%)
Similarity:	129/290 - (44%)	Gaps:	66/290 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 CS-PAVTQHGVITSSAGQVTSGTLDAVSAAP----ALPSLTASSSSHVEHKVRADKSTLDCATTS 214
            || .|...|..:.....|.:.......|||.    |.|.|:..|..:..|:...:...|..|.:|
Zfish   183 CSLTAPNPHSSLLRELFQTSDDAALLASAAELPACAKPQLSTVSVRYRSHEFTKNTPQLRTAGSS 247

  Fly   215 SHAAAPSSSSSASDHQQGRISGSKSSNTSGTGGGASASGGGGSALYSSYKSSWGSHSS---TQS- 275
            ...|:..|..||.:                                 ....|||||||   ||.
Zfish   248 GEQASQESVESAEE---------------------------------CVLRSWGSHSSLADTQRV 279

  Fly   276 ---QGYSSNALGIKHDPHSQ-----LRQPDPYQMFG----PTSSRLASSGSGQIQLWQFLLELLS 328
               ..:....|.:....|.:     :::.:..|..|    |.:.....:|||.|||||||||||:
Zfish   280 PSYDSFEEELLPLGLQKHGRSFKDYVQERNQTQETGRPVIPAAVLAGFTGSGPIQLWQFLLELLT 344

  Fly   329 DSNNASCITWEGTNGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYA 393
            ||...|.|:|.|...|||||||||||||||:||:||.|||:||||.|||||||||:.|..||||.
Zfish   345 DSTCQSIISWTGDGWEFKLTDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTSGKRYV 409

  Fly   394 YKF--DFQGLAAAT----------QPAASD 411
            |:|  |.|.|...|          ||.:.|
Zfish   410 YRFVCDLQNLLGYTVEELHGLLGVQPDSED 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ets65A	NP_001303373.1	ETS	316..401	CDD:197710	61/86 (71%)
ets2	NP_001018874.1	SAM_superfamily	76..164	CDD:301707
ets2	NP_001018874.1	ETS	332..416	CDD:197710	59/83 (71%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910