Protein Alignment Ets65A and ELK1

DIOPT Version :10

• Sequence 1: NP_001303373.1
• Gene: Ets65A / 38700
• FlyBaseID: FBgn0005658
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: NP_005220.2
• Gene: ELK1 / 2002
• HGNCID: 3321
• Length: 428
• Species: Homo sapiens
• Alignment Length: 199
• Identity: 76/199 - (38%)
• Similarity: 98/199 - (49%)
• Gaps: 27/199 - (13%)

  Fly   317 IQLWQFLLELLSDSNNASCITWEGTN-GEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYD 380
            :.||||||:||.:..|...|:|...: |||||.|.:||||.||.||:|.||||||||||||||||
Human     5 VTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLSRALRYYYD 69

  Fly   381 KNIMTKVHGKRYAYKF-DFQGLA-AATQPAASDPTYKYQSDLFMTPYHHSAKLSSFMSPHHGMTS 443
            |||:.||.|:::.||| .:..:| .:|:.....|.....|.:     .:.|..:...:|  |.|.
Human    70 KNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTM-----PNVAPAAIHAAP--GDTV 127

  Fly   444 SSASIFPSAASWGNWGSPA---------TNLY--------QPHSMSHVTPSHVAPHLSSYPHYAX 491
            |.....|..|.....|..|         :.||        ||....|..|:.|.|..:.....|
Human   128 SGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSLQPQPPPHPRPAVVLPSAAPAGAAAP 192

  Fly   492 PSSS 495
            ||.|
Human   193 PSGS 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ets65A	NP_001303373.1	ETS	316..401	CDD:197710	51/85 (60%)
ELK1	NP_005220.2	ETS	4..89	CDD:197710	51/83 (61%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..149		8/29 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	165..205		10/32 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	228..358
		Sufficient for interaction with MAD2L2. /evidence=ECO:0000269|PubMed:17296730	349..399