DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ets65A and Elk1

DIOPT Version :9

Sequence 1:NP_001303373.1 Gene:Ets65A / 38700 FlyBaseID:FBgn0005658 Length:728 Species:Drosophila melanogaster
Sequence 2:NP_031948.4 Gene:Elk1 / 13712 MGIID:101833 Length:429 Species:Mus musculus


Alignment Length:357 Identity:94/357 - (26%)
Similarity:135/357 - (37%) Gaps:127/357 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   317 IQLWQFLLELLSDSNNASCITWEGTN-GEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYD 380
            :.||||||:||.:..|...|:|...: |||||.|.:||||.||.||:|.||||||||||||||||
Mouse     5 VTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLSRALRYYYD 69

  Fly   381 KNIMTKVHGKRYAYKF-DFQGLA-AATQPAASDPTYKYQSDLFMTP------------------- 424
            |||:.||.|:::.||| .:..:| .:|:.....|.....|.:.|.|                   
Mouse    70 KNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSAIAMAPATVHAGPGDTATGKPGTPK 134

  Fly   425 -----------------YHHSAKLSSFM------SPHHGMTSSSASIFPSAASWG----NWGSPA 462
                             |..|...|:|.      .|...:....||:.|:....|    ..||.:
Mouse   135 GAGMTGQGGLARSSRNEYMRSGLYSTFTIQSLQPQPQPPIPPRPASVLPNTTPAGVPAPASGSRS 199

  Fly   463 TN--------------------LYQPHSMSHVTPSHVAPHLSSYPHYAXP--------------- 492
            |:                    |..|.:     |:..:..||..|.:..|               
Mouse   200 TSPNPLEACLEAEEAGLPLQVILTPPEA-----PNQKSEELSLDPSFGHPQPPEVKVEGPKEELE 259

  Fly   493 SSSGGAFXYES----NAIASASGI----------------GGGTASTGVGIGGVGG--------- 528
            ::..|.|..|:    ..::::.|:                |..|::|.:.....|.         
Mouse   260 AARAGGFSSEAVKAEPEVSASEGLLARLPAILTENTAQVCGLSTSTTEITQPQKGRKPRDLELPL 324

  Fly   529 ----AGGGG-----GSGVSTGVGSTSSSTTSS 551
                .||.|     |||.|:|:.:...:.|.|
Mouse   325 SPSLLGGQGPERTPGSGTSSGLQAPGPALTPS 356

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ets65ANP_001303373.1 ETS 316..401 CDD:197710 51/85 (60%)
Elk1NP_031948.4 ETS 4..89 CDD:197710 51/83 (61%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 119..146 0/26 (0%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 165..204 8/38 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 227..253 5/30 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 302..354 11/51 (22%)
Sufficient for interaction with MAD2L2. /evidence=ECO:0000250|UniProtKB:P19419 350..400 2/7 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3806
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.