DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10467 and YNR071C

DIOPT Version :9

Sequence 1:	NP_648026.1	Gene:	CG10467 / 38697	FlyBaseID:	FBgn0035679	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_014469.1	Gene:	YNR071C / 855808	SGDID:	S000005354	Length:	342	Species:	Saccharomyces cerevisiae

Alignment Length:	379	Identity:	99/379 - (26%)
Similarity:	153/379 - (40%)	Gaps:	96/379 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 KRFTLTNGAGMSVQLITRGATITSIKTPDASGQIDDVTLGFDDLAGYQSERNPYFGATIGRVCNR 89
            |:|..|        :...|||:..:|   .:||  .|..|:.::..|.::.| ..|||:||..||
Yeast    19 KKFQAT--------IAPLGATLVDLK---VNGQ--SVVQGYSNVQDYLTDGN-MMGATVGRYANR 69

  Fly    90 IANGSFYLDG---KLVQVSKNRDNKFQLHGGFVGFDKAHWEV--VEVRVDGVTL-------SHTN 142
            ||.|.|.||.   ||...:....|    |......:...::.  ||....||.:       .||.
Yeast    70 IAKGVFSLDDGPHKLTVNNCGNTN----HSSISSLNLKQYKASPVENPSKGVYVVEFKLLDDHTQ 130

  Fly   143 PDGHEGYPGKVTATASFTLSEDNC---LHVQMSALADKTTPVNLTNHSYFNLAGHKSGANGLYEH 204
            |:.:| :||.:..|..:||:....   :..|...:....||:|:||||||||...||      |.
Yeast   131 PNPNE-FPGDLEVTVKYTLNVAEMTLDMEYQAQLVRGDATPINMTNHSYFNLNKVKS------EK 188

  Fly   205 TI---EINA---YGITETDQSSIPTGRI-------------------TPVEGTGFDLRVSSNLGE 244
            :|   |:..   ..:..|:.:.:|||:|                   |||    ||.....:..:
Yeast   189 SIRGTEVKVCSNKSLEVTEGALLPTGKIIERNIATFDSTKPTVLHEDTPV----FDCTFIIDANK 249

  Fly   245 RLKALQPARGYDDNFCVTFSPPQPLAKVARATHPPSGRWLEVVSNQPGVQFYTSNFMPDVERGES 309
            .||.       .|:..|     ..|..|.:|.||.|....||.:.:|.|..||         |::
Yeast   250 DLKT-------TDSVSV-----NKLVPVFKAYHPESHIKFEVSTTEPTVHLYT---------GDN 293

  Fly   310 PIPGKDGAAYAKHCAFCLETQKFPDSVNHSNFPS-TILRPGESYQHEVIYKFGV 362
             :.||    :.....|.::..::.|::|...:.. .:|:.||.|..:..|||.:
Yeast   294 -LCGK----FVPRSGFAVQQGRYVDAINRDEWRGCVLLKRGEVYTSKTQYKFDI 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10467	NP_648026.1	galactose_mutarotase_like	26..360	CDD:185696	96/374 (26%)
YNR071C	NP_014469.1	galactose_mutarotase_like	13..340	CDD:185696	97/375 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344284
Domainoid	1	1.000	117	1.000	Domainoid score	I1291
eggNOG	1	0.900	-	-		E1_COG2017
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	105	1.000	Inparanoid score	I1419
Isobase	1	0.950	-	0.791477	Normalized mean entropy	S2151
OMA	1	1.010	-	-		QHG62696
OrthoFinder	1	1.000	-	-		FOG0001529
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101504
Panther	1	1.100	-	-	O	PTHR10091
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3159
SonicParanoid	1	1.000	-	-		X1103
TreeFam	0	0.000	Not matched by this tool.
	12	11.780