DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10467 and galm

DIOPT Version :9

Sequence 1:	NP_648026.1	Gene:	CG10467 / 38697	FlyBaseID:	FBgn0035679	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001002373.1	Gene:	galm / 436646	ZFINID:	ZDB-GENE-040718-66	Length:	342	Species:	Danio rerio

Alignment Length:	366	Identity:	176/366 - (48%)
Similarity:	225/366 - (61%)	Gaps:	29/366 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVNVTEDVFANGAVNPFTKSKDTIKRFTLTNGAGMSVQLITRGATITSIKTPDASGQIDDVTLGF 65
            |..|.::.|.. |:.|       ::|:.| ..|.:||::|:.|..|.||||.|.|||..|:.|||
Zfish     1 MTEVHKEEFGT-ALGP-------VERWIL-RSASVSVEIISLGCVIKSIKTADRSGQSADIVLGF 56

  Fly    66 DDLAGYQSERNP-YFGATIGRVCNRIANGSFYLDGKLVQVSKNRDNKFQLHGGFVGFDKAHW--E 127
            ||:.||.|  || ||||.:|||.|||:.|.|.:|.|..:::.| :....||||..|||||.|  |
Zfish    57 DDIEGYFS--NPRYFGAVVGRVANRISKGRFVIDEKEYKLAIN-NGPNALHGGLKGFDKAVWSTE 118

  Fly   128 VVEVRVDGVTLSHTNPDGHEGYPGKVTATASFTLSEDNCLHVQMSALADKTTPVNLTNHSYFNLA 192
            .|:   :||.|||::|||.|||||.:..:.::|| |.:.|.|...|..|.|||:|||||||||||
Zfish   119 AVD---NGVKLSHSSPDGDEGYPGNLKVSVTYTL-EKSTLSVLYHAQTDHTTPINLTNHSYFNLA 179

  Fly   193 GHKSGANGLYEHTIEINAYGITETDQSSIPTGRITPVEGTGFDLRVSSNLGERLKALQPARGYDD 257
            |  .|...:|:|.:.|:|......|.:.||||.:.|||.|.||||....||.|||.|. ..|:|.
Zfish   180 G--EGTPDIYDHEVTISAESYLPVDDTVIPTGEVKPVEKTPFDLRKPVILGFRLKELS-GPGFDH 241

  Fly   258 NFCVTFSPPQPL-AKVARATHPPSGRWLEVVSNQPGVQFYTSNFMPDVERGESPIPGKDGAAYAK 321
            |||:......|| .|.||..||.:||.|||.:.|||||||||||:      :..:.||.||||:|
Zfish   242 NFCLYLPGEPPLERKCARVVHPGTGRVLEVSTTQPGVQFYTSNFL------DGSVKGKGGAAYSK 300

  Fly   322 HCAFCLETQKFPDSVNHSNFPSTILRPGESYQHEVIYKFGV 362
            |.|||||||.:||:||..:||..:|||||:|.|...:.|.|
Zfish   301 HSAFCLETQNWPDAVNQPHFPDALLRPGETYSHTTRFTFSV 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10467	NP_648026.1	galactose_mutarotase_like	26..360	CDD:185696	169/337 (50%)
galm	NP_001002373.1	galactose_mutarotase_like	26..339	CDD:185696	166/328 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582912
Domainoid	1	1.000	296	1.000	Domainoid score	I1446
eggNOG	1	0.900	-	-		E1_COG2017
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	300	1.000	Inparanoid score	I2663
OMA	1	1.010	-	-		QHG62696
OrthoDB	1	1.010	-	-		D482699at33208
OrthoFinder	1	1.000	-	-		FOG0001529
OrthoInspector	1	1.000	-	-		otm24263
orthoMCL	1	0.900	-	-		OOG6_101504
Panther	1	1.100	-	-	LDO	PTHR10091
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1103
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770