Protein Alignment CG10469 and TPSB2

DIOPT Version :10

• Sequence 1: NP_648025.1
• Gene: CG10469 / 38696
• FlyBaseID: FBgn0035678
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_077078.5
• Gene: TPSB2 / 64499
• HGNCID: 14120
• Length: 275
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 80/277 - (28%)
• Similarity: 143/277 - (51%)
• Gaps: 26/277 - (9%)

  Fly     2 ILQLVLIVQFSLVF-----GQETGSLRIMNGTAAKAKQLPYQVGLLCYFEGSKDE--PNMCGGTI 59
            :|.|.|.|..|..:     ||....:.|:.|..|...:.|:||.|..     :|.  .:.|||::
Human     4 LLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRV-----RDRYWMHFCGGSL 63

  Fly    60 LSNRWIITAAHCLQDPKSNLWKVLIHVGKVK-SFDDKEIVVNRSYTIVHKKFDRKTVTNDIALIK 123
            :..:|::|||||:.....:|..:.:.:.:.. .:.|:.:.|:|  .|||.:|....:..||||::
Human    64 IHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSR--IIVHPQFYTAQIGADIALLE 126

  Fly   124 LPKKLTFNKYIQPAKLPSAKKTY-TGRKAIISGWG--LTTKQLPSQV-LQYIRAPIISNKECERQ 184
            |.:.:..:.::....||.|.:|: .|....::|||  ...::||... |:.::.||:.|..|:.:
Human   127 LEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAK 191

  Fly   185 WNKQLG---GKSKKVVHNGFICIDSKKGLPCRGDSGGPMVLD-DGSRTLVGIVSHGFDGECKLKL 245
            ::  ||   |...::|.:..:|..:.:...|:||||||:|.. :|:....|:||.| :|..:...
Human   192 YH--LGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNR 253

  Fly   246 PDVSTRVSSYLKWIKYY 262
            |.:.|||:.||.||.:|
Human   254 PGIYTRVTYYLDWIHHY 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	70/246 (28%)
TPSB2	NP_077078.5	Tryp_SPc	31..268	CDD:238113	71/246 (29%)