Protein Alignment CG10469 and CELA2A

DIOPT Version :10

• Sequence 1: NP_648025.1
• Gene: CG10469 / 38696
• FlyBaseID: FBgn0035678
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_254275.1
• Gene: CELA2A / 63036
• HGNCID: 24609
• Length: 269
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 84/273 - (30%)
• Similarity: 127/273 - (46%)
• Gaps: 25/273 - (9%)

  Fly     1 MILQLVL--IVQFSLVFGQETGS---LRIMNGTAAKAKQLPYQVGLLCYFEGSKDEPNMCGGTIL 60
            ||..|:|  :|..:|..|..|..   .|::.|..|:....|:||.|  .:..:....:.|||:::
Human     1 MIRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSL--QYSSNGKWYHTCGGSLI 63

  Fly    61 SNRWIITAAHCLQDPKSNLWKVLIHVGKVKSFDDKEIVVNRSYTIVHKKFDRKTVT--NDIALIK 123
            :|.|::|||||:.  .|..::|.:....:...:...:.|:.|..:|||.::...::  |||||:|
Human    64 ANSWVLTAAHCIS--SSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLK 126

  Fly   124 LPKKLTFNKYIQPAKLPSAKKTYTGR-KAIISGWG-LTTKQLPSQVLQYIRAPIISNKECERQ-- 184
            |...::....||.|.||.|....... ...::||| |.|......|||..|..::....|...
Human   127 LANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAW 191

  Fly   185 WNKQLGGKSKKVVHNGFICIDSKKGLPCRGDSGGPM--VLDDGSRTLVGIVSHGFDGECK-LKLP 246
            |...:  |:..:...|...|.|     |.||||||:  ...||...:.||||.|....|. ...|
Human   192 WGSSV--KTSMICAGGDGVISS-----CNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKP 249

  Fly   247 DVSTRVSSYLKWI 259
            .|.||||:|:.||
Human   250 SVFTRVSNYIDWI 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	74/244 (30%)
CELA2A	NP_254275.1	Tryp_SPc	29..265	CDD:238113	75/245 (31%)