Protein Alignment CG10469 and KLK10

DIOPT Version :10

• Sequence 1: NP_648025.1
• Gene: CG10469 / 38696
• FlyBaseID: FBgn0035678
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_002767.2
• Gene: KLK10 / 5655
• HGNCID: 6358
• Length: 276
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 73/251 - (29%)
• Similarity: 115/251 - (45%)
• Gaps: 55/251 - (21%)

  Fly    30 AKAKQLPYQVGLLCYFEGSKDEPNMCGGTILSNRWIITAAHCLQDPKSNLWKVLIHVGKVKSFDD 94
            |:..| |:||.|   |.|....   |.|.::...|::|||||...|   ||   ..||     ||
Human    53 ARGSQ-PWQVSL---FNGLSFH---CAGVLVDQSWVLTAAHCGNKP---LW---ARVG-----DD 99

  Fly    95 KEIVV------NRSYTIVHKKF--------DRKTVTNDIALIKLPKKLTFNKYIQPAKLPSAKKT 145
            ..:::      ..:.::||.|:        .|:|..:|:.|:||.:.:.....::..:|| .:..
Human   100 HLLLLQGEQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLP-YRCA 163

  Fly   146 YTGRKAIISGWGLTTKQLPSQVLQYIRA------PIISNKECERQWNKQLGGKSKKVVHNGFICI 204
            ..|.:..::|||.|.    ::.::|.:.      .|:|.||||..:        ..||.|..||.
Human   164 QPGDQCQVAGWGTTA----ARRVKYNKGLTCSSITILSPKECEVFY--------PGVVTNNMICA 216

  Fly   205 DSKKGL-PCRGDSGGPMVLDDGSRTLVGIVSHGFDGECKLKLPDVSTRVSSYLKWI 259
            ...:|. ||:.|||||:|.|:   ||.||:|.|.......:.|.|.|::..|:.||
Human   217 GLDRGQDPCQSDSGGPLVCDE---TLQGILSWGVYPCGSAQHPAVYTQICKYMSWI 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	71/249 (29%)
KLK10	NP_002767.2	Tryp_SPc	49..272	CDD:238113	73/251 (29%)