Protein Alignment CG10469 and TMPRSS9

DIOPT Version :10

• Sequence 1: NP_648025.1
• Gene: CG10469 / 38696
• FlyBaseID: FBgn0035678
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001382442.1
• Gene: TMPRSS9 / 360200
• HGNCID: 30079
• Length: 1093
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 87/262 - (33%)
• Similarity: 136/262 - (51%)
• Gaps: 39/262 - (14%)

  Fly    17 QETGS-------LRIMNGTAAKAKQLPYQVGLLCYFEGSKDEPNMCGGTILSNRWIITAAHCLQD 74
            ||.|:       .|::.|..|.:.::|:||.|.   |||:   :.||.|::.:||:::||||...
Human   524 QECGARPAMEKPTRVVGGFGAASGEVPWQVSLK---EGSR---HFCGATVVGDRWLLSAAHCFNH 582

  Fly    75 PKSNLWKVLIHVG--KVKSFDDKEIVVNRSYTIVHKKFDRKTVTNDIALIKLPKKLTFNKYIQPA 137
            .|  :.:|..|:|  .:.......:.:.....::|..::...:..|:|:::|...|.|||||||.
Human   583 TK--VEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPV 645

  Fly   138 KLPSA-KKTYTGRKAIISGWGLT-----TKQLPSQVLQYIRAPIISNKECERQWNKQLGGKSKKV 196
            .||.| :|...|||.:|||||.|     ||   .::||.....||..|.|...:|..|   :.::
Human   646 CLPLAIQKFPVGRKCMISGWGNTQEGNATK---PELLQKASVGIIDQKTCSVLYNFSL---TDRM 704

  Fly   197 VHNGFI--CIDSKKGLPCRGDSGGPMVLDD--GSRTLVGIVSHGFDGECKLKLPDVSTRVSSYLK 257
            :..||:  .:||     |:||||||:..::  |...|.||||.|. |..::|.|.|.||::....
Human   705 ICAGFLEGKVDS-----CQGDSGGPLACEEAPGVFYLAGIVSWGI-GCAQVKKPGVYTRITRLKG 763

  Fly   258 WI 259
            ||
Human   764 WI 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	82/247 (33%)
TMPRSS9	NP_001382442.1	SEA	66..>127	CDD:460188
		LDLa	188..223	CDD:238060
		Tryp_SPc	236..465	CDD:214473
		Tryp_SPc	538..768	CDD:238113	83/248 (33%)
		Pneumo_att_G	<717..>867	CDD:114270	22/50 (44%)
		Tryp_SPc	861..1087	CDD:238113