Protein Alignment CG10469 and PRSS48

DIOPT Version :10

• Sequence 1: NP_648025.1
• Gene: CG10469 / 38696
• FlyBaseID: FBgn0035678
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001340540.1
• Gene: PRSS48 / 345062
• HGNCID: 24635
• Length: 346
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 91/270 - (33%)
• Similarity: 133/270 - (49%)
• Gaps: 32/270 - (11%)

  Fly     5 LVLIVQFSLVFGQETGSLRIMNGTAAKAKQLPYQVGLLCYFEGSKDEPNMCGGTILSNRWIITAA 69
            |:|::..| |.||...|.|::.|..|.|.:.|:||.|  :|    |...:|||:::|.|.|:|||
Human    10 LLLLLGIS-VCGQPVYSSRVVGGQDAAAGRWPWQVSL--HF----DHNFICGGSLVSERLILTAA 67

  Fly    70 HCLQDPKSNLWKVLIHVGKVKSFDD-KEIVVNRSYTIVHKKFDRKTVTNDIALIKLPKKLTFNKY 133
            ||:| |....:...:.:|.:...|. |.:....|..::|.|:  :..|.|:||:||..::||...
Human    68 HCIQ-PTWTTFSYTVWLGSITVGDSRKRVKYYVSKIVIHPKY--QDTTADVALLKLSSQVTFTSA 129

  Fly   134 IQPAKLPSAKKTYTGRKAI-----ISGWGLTTKQLP---SQVLQYIRAPIISNKECERQWNKQLG 190
            |.|..|||..|    :.||     ::|||...:...   ...||....|||..:.||:.:| .:|
Human   130 ILPICLPSVTK----QLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYN-PIG 189

  Fly   191 ---GKSKKVVHNGFICIDSKKGL--PCRGDSGGPMVLD-DGSRTLVGIVSHGFDGECKLKLPDVS 249
               ...:.|:....||....:.:  .|:||||||:... ||.....|:||.|.  ||...||.|.
Human   190 IFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGL--ECGKSLPGVY 252

  Fly   250 TRVSSYLKWI 259
            |.|..|.|||
Human   253 TNVIYYQKWI 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	82/250 (33%)
PRSS48	NP_001340540.1	Tryp_SPc	28..265	CDD:238113	83/251 (33%)