Protein Alignment CG10469 and GZMK

DIOPT Version :10

• Sequence 1: NP_648025.1
• Gene: CG10469 / 38696
• FlyBaseID: FBgn0035678
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 69/258 - (26%)
• Similarity: 107/258 - (41%)
• Gaps: 44/258 - (17%)

  Fly    21 SLRIMNGTAAKAKQLPYQVGLLCYFEGSKDEPNMCGGTILSNRWIITAAHCL------QDPKSNL 79
            ::.|:.|........|:...:  .:.|.    ::|||.::..:|::|||||.      |.|
Human    24 NMEIIGGKEVSPHSRPFMASI--QYGGH----HVCGGVLIDPQWVLTAAHCQYRFTKGQSP---- 78

  Fly    80 WKVLIHVGKVKSFDDKEIVVNRSYTIVHKK---FDRKT---VTNDIALIKLPKKLTFNKYIQPAK 138
               .:.:| ..|....|.   ...|:..||   |.|.|   .:|||.|:||......||:::...
Human    79 ---TVVLG-AHSLSKNEA---SKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLH 136

  Fly   139 LPSAKKTYTGRKAIISGWGLTTKQ--LPSQVLQYIRAPIISNKECERQWNKQLGGKSKKVVHNGF 201
            :.|.....:|.|..::|||.|...  .||..|:.:...::|.|.|    |.|........:....
Human   137 IRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLC----NSQSYYNGDPFITKDM 197

  Fly   202 ICIDSKKGL--PCRGDSGGPMVLDDGSRTLVGIVSHGFDGECKLKL-PDVSTRVS-SYLKWIK 260
            :|....||.  .|:||||||::.   ......|||.|.  ||.:.. |.:.|.:: .|..|||
Human   198 VCAGDAKGQKDSCKGDSGGPLIC---KGVFHAIVSGGH--ECGVATKPGIYTLLTKKYQTWIK 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	66/253 (26%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	69/255 (27%)