DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10469 and CG30187

DIOPT Version :9

Sequence 1:	NP_648025.1	Gene:	CG10469 / 38696	FlyBaseID:	FBgn0035678	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_001246475.2	Gene:	CG30187 / 246509	FlyBaseID:	FBgn0050187	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	230	Identity:	71/230 - (30%)
Similarity:	104/230 - (45%)	Gaps:	51/230 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 MCGGTILSNRWIITAAHCL--QDPKSNLWKVLIHVGKVKSFD--DKEIVVNRSYTIVHKKFD-RK 113
            :||||::..|:::|||||:  ||.:|      :.:|.....|  |::.|:.   .:||..|| |.
  Fly    60 ICGGTLIHKRFVLTAAHCIVDQDVQS------VSLGAYNKSDPADRKDVIT---AVVHSSFDVRA 115

  Fly   114 TVTNDIALIKLPKKLTFNKYIQPAKLPSAK---------KTYTGRKAIISGWGLTTKQLPSQVLQ 169
            :..|||.|:||...:.||..|:|..:...|         :|:   ||.  |||.......|.:||
  Fly   116 SYENDIGLLKLSSDVIFNALIRPICIVLNKSMANHMRNMRTF---KAF--GWGTLRGNKTSDILQ 175

  Fly   170 YIRAPIISNKECERQWNKQLGGKSKKVVHNGFICIDSKKGLPCRGDSGGPMVLD-----DGSRTL 229
            .|....:..:||..:.:.....|.        ||.....|..|.||||||:..|     .|:|.:
  Fly   176 TIILNHLDREECYMELSVYPSEKQ--------ICAGVPSGDTCGGDSGGPLTNDVFIQGIGNREV 232

  Fly   230 -VGIVSHG---FDGECKLKLPDVSTRVSSYLKWIK 260
             .||:|.|   .||:      .|.|.:.|:..|||
  Fly   233 QFGIISVGKTSCDGQ------GVYTDLMSFADWIK 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	68/227 (30%)
CG10469	NP_648025.1	Tryp_SPc	24..260	CDD:238113	69/228 (30%)
CG30187	NP_001246475.2	Tryp_SPc	35..260	CDD:214473	68/227 (30%)
CG30187	NP_001246475.2	Trypsin	316..>384	CDD:355628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010