DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10469 and Cela2a

DIOPT Version :9

Sequence 1:	NP_648025.1	Gene:	CG10469 / 38696	FlyBaseID:	FBgn0035678	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_036685.1	Gene:	Cela2a / 24332	RGDID:	2548	Length:	271	Species:	Rattus norvegicus

Alignment Length:	275	Identity:	86/275 - (31%)
Similarity:	130/275 - (47%)	Gaps:	27/275 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MILQLVL--IVQFSLVFGQETGSL-----RIMNGTAAKAKQLPYQVGLLCYFEGSKDEPNMCGGT 58
            ||..|:|  :|..:|..|..|..:     |::.|..|.....|:||.|. |....|.. :.|||:
  Rat     1 MIRTLLLSALVAGALSCGYPTYEVQHDVSRVVGGQEASPNSWPWQVSLQ-YLSSGKWH-HTCGGS 63

  Fly    59 ILSNRWIITAAHCLQDPKSNLWKVLIHVGKVKSFDDKEIVVNRSYTIVHKKFDRKTVT--NDIAL 121
            :::|.|::|||||:.:  |..::||:....:.:.:...:.|..|..:||:|::.:.::  |||||
  Rat    64 LVANNWVLTAAHCISN--SRTYRVLLGRHSLSTSESGSLAVQVSKLVVHEKWNAQKLSNGNDIAL 126

  Fly   122 IKLPKKLTFNKYIQPAKLPSAKKTYTGR-KAIISGWG-LTTKQLPSQVLQYIRAPIISNKECERQ 184
            :||...:.....||.|.||.|....... ...::||| |.|......|||..|..::....|...
  Rat   127 VKLASPVALTSKIQTACLPPAGTILPNNYPCYVTGWGRLQTNGATPDVLQQGRLLVVDYATCSSA 191

  Fly   185 --WNKQLGGKSKKVVHNGFICIDSKKGLPCRGDSGGPM--VLDDGSRTLVGIVSHGFDGECKL-K 244
              |...:  |:..|...|.....|     |.||||||:  ...:|...:.||||.|....|.. :
  Rat   192 SWWGSSV--KTNMVCAGGDGVTSS-----CNGDSGGPLNCQASNGQWQVHGIVSFGSTLGCNYPR 249

  Fly   245 LPDVSTRVSSYLKWI 259
            .|.|.||||:|:.||
  Rat   250 KPSVFTRVSNYIDWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	76/244 (31%)
CG10469	NP_648025.1	Tryp_SPc	24..260	CDD:238113	77/245 (31%)
Cela2a	NP_036685.1	Tryp_SPc	30..264	CDD:214473	76/244 (31%)
Cela2a	NP_036685.1	Tryp_SPc	31..267	CDD:238113	77/245 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	143	1.000	Inparanoid score	I4367
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960