Protein Alignment CG10469 and CFD

DIOPT Version :10

• Sequence 1: NP_648025.1
• Gene: CG10469 / 38696
• FlyBaseID: FBgn0035678
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 70/270 - (25%)
• Similarity: 125/270 - (46%)
• Gaps: 39/270 - (14%)

  Fly     6 VLIVQFSLVFGQETGSL------RIMNGTAAKAKQLPYQVGLLCYFEGSKDEPNMCGGTILSNRW 64
            ||::..:...|:|..:.      ||:.|..|:|...||...:  ...|:    ::|||.:::.:|
Human     9 VLVLLGAAACGEEAWAWAAPPRGRILGGREAEAHARPYMASV--QLNGA----HLCGGVLVAEQW 67

  Fly    65 IITAAHCLQDPKSNLWKVLIHVGKVKSFDDKEIVVNRSYTIVHKKFDRKTVTNDIALIKLPKKLT 129
            :::|||||:|......:||:....:...:..:.:.:....:.|......|:.:|:.|::|.:|.|
Human    68 VLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKAT 132

  Fly   130 FNKYIQPAKLP---SAKKTYTGRKAIISGWGLTTK--QLPSQVLQYIRAPIISNKECERQWNKQL 189
            ....::|  ||   ..:....|....::|||:...  :.|.. ||::..|::....|.|:.:
Human   133 LGPAVRP--LPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDS-LQHVLLPVLDRATCNRRTH--- 191

  Fly   190 GGKSKKVVHNGFI-----CIDSKKGLPCRGDSGGPMVLDDGSRTLVGIVSHGFDGECKLKLPDVS 249
                    |:|.|     |.:|.:...|:||||||:|.   ...|.|:|:.|.......|.|.:.
Human   192 --------HDGAITERLMCAESNRRDSCKGDSGGPLVC---GGVLEGVVTSGSRVCGNRKKPGIY 245

  Fly   250 TRVSSYLKWI 259
            |||:||..||
Human   246 TRVASYAAWI 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	64/245 (26%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	65/246 (26%)