Protein Alignment CG10469 and CTSG

DIOPT Version :10

• Sequence 1: NP_648025.1
• Gene: CG10469 / 38696
• FlyBaseID: FBgn0035678
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: XP_011534801.1
• Gene: CTSG / 1511
• HGNCID: 2532
• Length: 269
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 68/272 - (25%)
• Similarity: 132/272 - (48%)
• Gaps: 38/272 - (13%)

  Fly     5 LVLIVQFSLVFGQETGSL------------RIMNGTAAKAKQLPYQVGLLCYFE-GSKDEPNMCG 56
            |:|::.|.|..|.|.||.            .|:.|..::....||    :.|.: .|....:.||
Human     4 LLLLLAFLLPTGAEAGSASIELSAKCFLPGEIIGGRESRPHSRPY----MAYLQIQSPAGQSRCG 64

  Fly    57 GTILSNRWIITAAHCLQDPKSNLWKVLIHVGKVKSFDDKEIVVNRSYTIVHKKFDRKTVTNDIAL 121
            |.::...:::|||||.   .||: .|.:....::..::.:..:.....|.|.:::::|:.|||.|
Human    65 GFLVREDFVLTAAHCW---GSNI-NVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIML 125

  Fly   122 IKLPKKLTFNKYIQPAKLPSAKK-TYTGRKAIISGWGLTTKQLPSQVLQYIRAPIISNKECERQW 185
            ::|.:::..|:.:.|..||.|:: ...|....::|||..:.:..:..|:.::..:..:::|.|.:
Human   126 LQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIF 190

  Fly   186 NKQLGGKSKKVVHNGFICIDSKKGLPC--RGDSGGPMVLDDGSRTLVGIVSHGFDGECKLKLPDV 248
            ......:.        ||:..::....  :||||||::.::.:.   ||||:|......   |:|
Human   191 GSYDPRRQ--------ICVGDRRERKAAFKGDSGGPLLCNNVAH---GIVSYGKSSGVP---PEV 241

  Fly   249 STRVSSYLKWIK 260
            .|||||:|.||:
Human   242 FTRVSSFLPWIR 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	58/239 (24%)
CTSG	XP_011534801.1	Tryp_SPc	35..255	CDD:238113	60/241 (25%)