DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10469 and CG42694

DIOPT Version :9

Sequence 1:	NP_648025.1	Gene:	CG10469 / 38696	FlyBaseID:	FBgn0035678	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_001188994.1	Gene:	CG42694 / 10178792	FlyBaseID:	FBgn0261584	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	265	Identity:	61/265 - (23%)
Similarity:	103/265 - (38%)	Gaps:	57/265 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 IMNGTAAKAKQLPYQVGLLCYFEGSKDEPNMCGGTILSNRWIITAAHCLQDPKSNLWKVLIHVGK 88
            |.|.:..|.:| | |.|.|.:.  |.....:|.|:::|.:::::||.|: |...   |:.:.:|
  Fly    31 ISNQSITKLRQ-P-QAGWLAHI--SNGTHVLCSGSLISKQFVLSAAQCI-DVHG---KLFVQLG- 86

  Fly    89 VKSFDDKEIVVNRS-----YT---IVHKKFDRKTVTNDIALIKLPKKLTFNKYIQPAKLPSAKKT 145
                     |.|.:     ||   :|......|.:..||.|:||.:.:.:|.::.|..:.....|
  Fly    87 ---------VSNATKSPHWYTVSNVVIPSHSGKRLQRDIGLLKLSQSVDYNDFVYPICIALNTNT 142

  Fly   146 YTGRKAI----ISGWGLTTKQLPSQVLQYIRAPIISNKECERQWNKQLGGKSKKVVHNGFICIDS 206
            ....|.:    .|.|....|...:.||..     :|...|:...:..:..|.        ||..|
  Fly   143 LDMVKILQNFTTSAWLSKNKNPQTIVLSQ-----LSRDRCKLNLSGNVTPKE--------ICAAS 194

  Fly   207 -KKGLPCRGDSGGPMV--LDDGS----RTLVGIVSHGF-DGECKLKLPDVSTRVSSYLKWI---- 259
             ::...|..|||..:.  :..||    ..|.||  .|: :|......|.:...|:..:.||
  Fly   195 LQRNNSCFIDSGSALTQPIIQGSNIVREMLFGI--RGYVNGRSWCSEPAIYIDVAECVGWIETVV 257

  Fly   260 KYYSG 264
            :.|.|
  Fly   258 QQYDG 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	57/254 (22%)
CG10469	NP_648025.1	Tryp_SPc	24..260	CDD:238113	59/259 (23%)
CG42694	NP_001188994.1	Tryp_SPc	46..256	CDD:304450	52/240 (22%)
		Tryp_SPc	46..253	CDD:214473	50/237 (21%)
		Tryp_SPc	319..505	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436477
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030