DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13293 and AT4G40050

DIOPT Version :9

Sequence 1:	NP_001261464.1	Gene:	CG13293 / 38695	FlyBaseID:	FBgn0035677	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_568079.1	Gene:	AT4G40050 / 830168	AraportID:	AT4G40050	Length:	599	Species:	Arabidopsis thaliana

Alignment Length:	639	Identity:	199/639 - (31%)
Similarity:	299/639 - (46%)	Gaps:	118/639 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FCHLLEKSKQLFNGLRDLPQYGHRQWQAYFGRTFDVYTKLWKFQQQHRMVLDSKYGLKRWQIGEI 82
            |..|:|.:.:.|..:||||.:|..| ..||.:.|..|.|||.:||.||..| .:.||.||:||||
plant    10 FRALVENADRKFARVRDLPAFGRAQ-SHYFQKVFKAYMKLWNYQQSHRSKL-VESGLNRWEIGEI 72

  Fly    83 ASKIGQLYYHYYLRTSETNYLNEAYQFYAAIRGRAYYSRAAKEDRPDLMVKKLRYYARFIVVCLL 147
            ||:|||||:..|:||||..:|.||:.||.||..|:|:..|..:|. ....|:||:||||::|.|:
plant    73 ASRIGQLYFSQYMRTSEARFLLEAFVFYEAILKRSYFDEAQGKDL-GARFKELRFYARFLLVSLI 136

  Fly   148 LKKMKLVRELVTELEKQIQEFPRSYEPEDHLEWSLVLEEIKGFIKAEAAVAVLHADSNPI----- 207
            :.:.:::..|..:|...:.....::...:..||.||::||..||:::..:..|    .|:
plant   137 VDRKQMLLHLADKLRLLVDHSISNFRETNFKEWRLVVQEITRFIESDTNLTYL----RPLRYCAM 197

  Fly   208 ILSHSGSGSRLSPLTTPPCERSPHMTLSLQEILIVGSACEQAKFSELTMDMFRMLQTLE------ 266
            :.|:..|.:.|:..       ........::.|:......:.|::|:|:|.:||:|.||
plant   198 LDSYPASQTYLARF-------HAKKLFKFRDALLASYHRNEVKYAEVTLDTYRMMQCLEWEPSGS 255

  Fly   267 ---REPTESTTNPLSMAHGLHGH--DASPAASRIPPYGVPGSKGYMENGRAFRDNPHKYLLYKPS 326
               ::|.|:..|...:.|.|...  |.:.||....|...|              ||.|.:||:|:
plant   256 FYQKKPVEAKENGFVVDHTLTSGLIDMNLAADMADPSLPP--------------NPRKAILYRPT 306

  Fly   327 ISQLLVFLASGSKELPLGGALLLYMSADG--CFSTTKHPEDFGYELGGLATSVKRDSVDGGGLSC 389
            :|.||..||....||.....:|||:||.|  .......||:   .:|...||..:       |..
plant   307 VSHLLAVLAMICDELSPETVMLLYLSASGGPARENVAQPEN---SVGSSRTSKSK-------LLA 361

  Fly   390 RG----KSYK---------------ENHC-------------LYPGDLYPFTRRPMFVVIDSDNS 422
            |.    ||||               |||.             ||||||.||||:|:|::||||.|
plant   362 RASQEQKSYKSEPHSNGKLMSAEYYENHLWLGPRGGSSGSNNLYPGDLIPFTRKPLFLIIDSDTS 426

  Fly   423 FVFQHI---PRYFGQPLVVLMSPQDVPPAFQ----ADVQH-HGSLFTLFLHSPLTALCYICNVGD 479
            ..|:.:   .|  |:|:.:|:||  :.|:|:    .|.:. :||.||.||.:||.|.|.:..:.:
plant   427 RAFKVLGGAER--GEPVAMLLSP--LKPSFENPSTDDTEALNGSQFTFFLTAPLQAFCQMLGLSN 487

  Fly   480 VPIHHWERCQTYVDRFITEASRLVTRCRIDEIEQGI---GFIDSSYVQFFGDDFLRTLILRFVFC 541
                      |..|..:.:.:..:......|.|..:   ..::..:.|...|.|||.|||||:||
plant   488 ----------TKPDPELCDEAESILSASFSEWETILLTSKVLNLVWAQVLPDPFLRRLILRFIFC 542

  Fly   542 -DVVLRLHRGFRGRHMRPRCEPQLPANELLEHPS--LSHIIFQLASALDVRGHF 592
             .|:....|........|:|.|.||  |||...|  :...:.:||..|.|...|
plant   543 RSVLTSFSRTEDDDPYLPQCHPNLP--ELLSSVSKPVQSSVQRLAEHLGVAKSF 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13293	NP_001261464.1	SCAI	20..551	CDD:403333	184/592 (31%)
AT4G40050	NP_568079.1	DUF3550	12..552	CDD:288889	183/591 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	298	1.000	Domainoid score	I341
eggNOG	1	0.900	-	-		E1_2CMAJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	317	1.000	Inparanoid score	I720
OMA	1	1.010	-	-		QHG55716
OrthoDB	1	1.010	-	-		D346932at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2410
orthoMCL	1	0.900	-	-		OOG6_104773
Panther	1	1.100	-	-	O	PTHR21243
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4469
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.840