DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13293 and scai

DIOPT Version :9

Sequence 1:	NP_001261464.1	Gene:	CG13293 / 38695	FlyBaseID:	FBgn0035677	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	XP_021332187.1	Gene:	scai / 556383	ZFINID:	ZDB-GENE-060526-57	Length:	578	Species:	Danio rerio

Alignment Length:	588	Identity:	297/588 - (50%)
Similarity:	398/588 - (67%)	Gaps:	31/588 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DRKLVLEFCHLLEKSKQLFNGLRDLPQYGHRQWQAYFGRTFDVYTKLWKFQQQHRMVLDSKYGLK 75
            :||.|.:||:||:|||||||||||||||||:|||:||||||||||||||||||||.|||::||||
Zfish    14 ERKTVTDFCYLLDKSKQLFNGLRDLPQYGHKQWQSYFGRTFDVYTKLWKFQQQHRQVLDNRYGLK 78

  Fly    76 RWQIGEIASKIGQLYYHYYLRTSETNYLNEAYQFYAAIRGRAYYSRAAKEDRPDLMVKKLRYYAR 140
            ||||||:||||||||||||||||||:|||||:.||:|||.|:||.:..|||||:|:|||||||||
Zfish    79 RWQIGEVASKIGQLYYHYYLRTSETSYLNEAFSFYSAIRQRSYYHQVNKEDRPELVVKKLRYYAR 143

  Fly   141 FIVVCLLLKKMKLVRELVTELEKQIQEFPRSYEPEDHLEWSLVLEEIKGFIKAEAAVAVLHADSN 205
            ||||||||.||.||:.||.||.::|:::.:.:..||.|||:|||:|:..|::|: .:.:|:.|:.
Zfish   144 FIVVCLLLNKMDLVKVLVKELSEEIEDYTQRFNTEDQLEWNLVLQEVAAFVEAD-PLMILNDDNA 207

  Fly   206 PIILSHSGSGSRLSPLTTPPCERSPHM-TLSLQEILIVGSACEQAKFSELTMDMFRMLQTLEREP 269
            .::||     :||.....||.|:...: .|:|.:.||||:...|.||||||:|||||||.|||||
Zfish   208 VVVLS-----NRLQEGGVPPLEQGMVVGQLTLADALIVGNCNNQVKFSELTIDMFRMLQALEREP 267

  Fly   270 TESTTNPLSMAHGLHGHDASPAA-SRIPPYGVPGSKGYMENGR-AFRDNPHKYLLYKPSISQLLV 332
            ....|           ..:.|.. .|...|.:|.:. |..|.: |.|:||||||||||:.|||..
Zfish   268 VNLAT-----------QSSKPGTLVREDSYTLPVTL-YEPNEKPAKRENPHKYLLYKPTFSQLYT 320

  Fly   333 FLASGSKELPLGGALLLYMSADGCFSTTKHPEDFGYELGGLATSVKRDSVDGGGLSCRGKSYKEN 397
            ||::..||||....||:|:||.|.|.|.:...:..|:.||:.|:..||.|:|..:..|.::.||.
Zfish   321 FLSASFKELPANSVLLVYLSATGVFPTGRSESEGPYDFGGVLTNTNRDVVNGETVQKRNQAQKEM 385

  Fly   398 HCLYPGDLYPFTRRPMFVVIDSDNSFVFQHIPRYFGQPLVVLMSPQDVPPAFQADVQHHGSLFTL 462
            |||:||||:||||:|:|:::||.||..:::....||||||.|:||...|.:.| |....||||||
Zfish   386 HCLHPGDLFPFTRKPLFIIVDSSNSTAYKNFSNLFGQPLVCLLSPTVYPKSMQ-DQSQRGSLFTL 449

  Fly   463 FLHSPLTALCYICNVGDVPIHHWERCQTYVDRFITEASRLVTRCRIDEIEQGIGFIDSSYVQFFG 527
            ||::||.....:|.:..:....||:.|..:.:...:..:::|..|:         ||.:|:||:|
Zfish   450 FLYNPLMGFLSVCGLSSMRYGLWEKAQELLRKVFHDIGQMITSSRV---------IDQAYLQFYG 505

  Fly   528 DDFLRTLILRFVFCDVVLRLHRGFRGRHMRPRCEPQLPANELLEHPSLSHIIFQLASALDVRGHF 592
            |:|||.|::|||||...||||:.||.....|...|.||..|::|...|...:.:||:.|||:..|
Zfish   506 DEFLRLLMIRFVFCSSALRLHKLFREARSFPESYPPLPKQEMVESSLLQKHVLELAAMLDVQNLF 570

  Fly   593 SEG 595
            |:|
Zfish   571 SDG 573

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13293	NP_001261464.1	SCAI	20..551	CDD:403333	275/533 (52%)
scai	XP_021332187.1	SCAI	23..529	CDD:314879	275/533 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576168
Domainoid	1	1.000	525	1.000	Domainoid score	I278
eggNOG	1	0.900	-	-		E1_2CMAJ
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15523
Inparanoid	1	1.050	565	1.000	Inparanoid score	I1040
OMA	1	1.010	-	-		QHG55716
OrthoDB	1	1.010	-	-		D301611at33208
OrthoFinder	1	1.000	-	-		FOG0007027
OrthoInspector	1	1.000	-	-		oto38813
orthoMCL	1	0.900	-	-		OOG6_104773
Panther	1	1.100	-	-	LDO	PTHR21243
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5609
SonicParanoid	1	1.000	-	-		X4469
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800