Protein Alignment CG13293 and SCAI

DIOPT Version :9

• Sequence 1: NP_001261464.1
• Gene: CG13293 / 38695
• FlyBaseID: FBgn0035677
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_775961.2
• Gene: SCAI / 286205
• HGNCID: 26709
• Length: 629
• Species: Homo sapiens
• Alignment Length: 585
• Identity: 299/585 - (51%)
• Similarity: 397/585 - (67%)
• Gaps: 40/585 - (6%)

  Fly    11 DRKLVLEFCHLLEKSKQLFNGLRDLPQYGHRQWQAYFGRTFDVYTKLWKFQQQHRMVLDSKYGLK 75
            :||.|.:||:||:||||||||||||||||.:|||:||||||||||||||||||||.|||::||||
Human    78 ERKTVTDFCYLLDKSKQLFNGLRDLPQYGQKQWQSYFGRTFDVYTKLWKFQQQHRQVLDNRYGLK 142

  Fly    76 RWQIGEIASKIGQLYYHYYLRTSETNYLNEAYQFYAAIRGRAYYSRAAKEDRPDLMVKKLRYYAR 140
            |||||||||||||||||||||||||:|||||:.||:|||.|:|||:..|||||:|:|||||||||
Human   143 RWQIGEIASKIGQLYYHYYLRTSETSYLNEAFSFYSAIRQRSYYSQVNKEDRPELVVKKLRYYAR 207

  Fly   141 FIVVCLLLKKMKLVRELVTELEKQIQEFPRSYEPEDHLEWSLVLEEIKGFIKAEAAVAVLHADSN 205
            ||||||||.||.:|::||.||..:|:::...:..||.:||:|||:|:..||:|: .|.||:.|:.
Human   208 FIVVCLLLNKMDVVKDLVKELSDEIEDYTHRFNTEDQVEWNLVLQEVAAFIEAD-PVMVLNDDNT 271

  Fly   206 PIILSHSGSGSRLSPLTTPPCERSPHM-TLSLQEILIVGSACEQAKFSELTMDMFRMLQTLEREP 269
            .:|.|     :||:....|..|:...: .|||.:.||:|:...|.||||||:|||||||.||||
Human   272 IVITS-----NRLAETGAPLLEQGMIVGQLSLADALIIGNCNNQVKFSELTVDMFRMLQALERE- 330

  Fly   270 TESTTNPLSMAHGLHGHDASPAASRIPPYGVPGSKGYMENGRAFRDNPHKYLLYKPSISQLLVFL 334
                  |:::|..::......:|.:                ...|:||||||||||:.|||..||
Human   331 ------PMNLASQMNKPGMQESADK----------------PTRRENPHKYLLYKPTFSQLYTFL 373

  Fly   335 ASGSKELPLGGALLLYMSADGCFSTTKHPEDFGYELGGLATSVKRDSVDGGGLSCRGKSYKENHC 399
            |:..||||....||:|:||.|.|.|.:...:..|:.||:.|:..||.::|..:..|.:|:||.||
Human   374 AASFKELPANSVLLIYLSATGVFPTGRSDSEGPYDFGGVLTNSNRDIINGDAIHKRNQSHKEMHC 438

  Fly   400 LYPGDLYPFTRRPMFVVIDSDNSFVFQHIPRYFGQPLVVLMSPQDVPPAFQADVQHHGSLFTLFL 464
            |:|||||||||:|:|:::||.||..:::....||||||.|:||...|.|.| |....||||||||
Human   439 LHPGDLYPFTRKPLFIIVDSSNSVAYKNFTNLFGQPLVCLLSPTAYPKALQ-DQSQRGSLFTLFL 502

  Fly   465 HSPLTALCYICNVGDVPIHHWERCQTYVDRFITEASRLVTRCRIDEIEQGIGFIDSSYVQFFGDD 529
            ::||.|..::..:..:....||:||.|:.:...:.::|:|..|         .||.:::|||||:
Human   503 NNPLMAFLFVSGLSSMRRGLWEKCQEYLRKINRDIAQLLTHSR---------SIDQAFLQFFGDE 558

  Fly   530 FLRTLILRFVFCDVVLRLHRGFRGRHMRPRCEPQLPANELLEHPSLSHIIFQLASALDVRGHFSE 594
            |||.|:.||:||...:|:|:.||.....|...||||.:|.:|:|.|...|.:|||.||||..|.|
Human   559 FLRLLLTRFIFCSATMRMHKIFRETRNYPESYPQLPRDETVENPHLQKHILELASILDVRNVFFE 623

  Fly   595  594
            Human   624  623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13293	NP_001261464.1	SCAI	20..551	CDD:403333	273/531 (51%)
SCAI	NP_775961.2	SCAI	87..580	CDD:403333	273/531 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143305
Domainoid	1	1.000	535	1.000	Domainoid score	I271
eggNOG	1	0.900	-	-		E1_2CMAJ
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15523
Inparanoid	1	1.050	581	1.000	Inparanoid score	I1023
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55716
OrthoDB	1	1.010	-	-		D301611at33208
OrthoFinder	1	1.000	-	-		FOG0007027
OrthoInspector	1	1.000	-	-		oto89962
orthoMCL	1	0.900	-	-		OOG6_104773
Panther	1	1.100	-	-	LDO	PTHR21243
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5609
SonicParanoid	1	1.000	-	-		X4469
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800