Protein Alignment ssp6 and LNX1

DIOPT Version :9

• Sequence 1: NP_001286952.1
• Gene: ssp6 / 38694
• FlyBaseID: FBgn0035676
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001119800.1
• Gene: LNX1 / 84708
• HGNCID: 6657
• Length: 728
• Species: Homo sapiens
• Alignment Length: 458
• Identity: 87/458 - (18%)
• Similarity: 142/458 - (31%)
• Gaps: 157/458 - (34%)

  Fly    10 CQSI-ATAASSAATTAAAVSISASNATSVGSLIAAACQQEQPHPHQHYSQSQQQHLYHQSHQQAS 73
            |.|: |||.|...:.||.:|:.............::.:..||                    ..|
Human   152 CASLTATAPSPEVSAAATISLMTDEPGLDNPAYVSSAEDGQP--------------------AIS 196

  Fly    74 HYVNGTGSLGRLK-FHKSLDASDEEIEYAQLSRSTHILGRHKSERYLASNPDEDRRRRTIIVEKK 137
            ...:|..:..|.: |.:|...|.   .:.:::|:..:|.|.||...:|::.|:.|       |..
Human   197 PVDSGRSNRTRARPFERSTIRSR---SFKKINRALSVLRRTKSGSAVANHADQGR-------ENS 251

  Fly   138 NNSYGFTLQSYGIHYKRDEELE--MITYVDYVE------YGGP-----------AYRAG------ 177
            .|:....:.....|...|.|:.  .|..||..|      .||.           .||.|
Human   252 ENTTAPEVFPRLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDG 316

  Fly   178 -MREGDVILSINGKDMEKADHKTIVEFIKQCDTRMRMVVLFEDCVRKVDLHMRYIQLQSMLQQKM 241
             :..||:||.:||.|:....|...|..::|            .|        :.:.|..|.:||.
Human   317 RLLPGDIILKVNGMDISNVPHNYAVRLLRQ------------PC--------QVLWLTVMREQKF 361

  Fly   242 NELERVHLRERELLEGKWKTHSLPARKKANANTSPSDGEGVSPTEVAGEAGFYRP------ALST 300
            .                                  |...|.:|..       |||      .:..
Human   362 R----------------------------------SRNNGQAPDA-------YRPRDDSFHVILN 385

  Fly   301 EDVPNIAARQHGVGGPGIIPPPAQFMLTYHYLDPTYRYVLRPTHGSSEE-----FVDGLGLQRSS 360
            :..|.   .|.|:.....:..|..|:  ::.||....|    .||..||     .::|..|:..|
Human   386 KSSPE---EQLGIKLVRKVDEPGVFI--FNVLDGGVAY----RHGQLEENDRVLAINGHDLRYGS 441

  Fly   361 SDHQPPAQRYVLQQTES----VDANSMTQPTTTAPTQYHSTTGGSVKP----------PAPPPRT 411
                |.:..:::|.:|.    |.:..:.|.:.....:....:.||..|          |..|..|
Human   442 ----PESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGERSNTPKPLHPTIT 502

  Fly   412 CEK 414
            |.:
Human   503 CHE 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	24/111 (22%)
LNX1	NP_001119800.1	mRING-HC-C3HC3D_LNX1	38..79	CDD:319693
		modified RING-HC finger (C3HC3D-type)	41..78	CDD:319693
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	178..214		6/55 (11%)
		NPXY motif	181..184		0/2 (0%)
		Interaction with MAGEB18. /evidence=ECO:0000269|PubMed:20864041	186..244		14/80 (18%)
		PDZ_signaling	272..355	CDD:238492	21/102 (21%)
		PDZ_signaling	380..460	CDD:238492	18/92 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	475..494		3/18 (17%)
		PDZ_signaling	505..588	CDD:238492	0/1 (0%)
		PDZ_signaling	637..721	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900