Protein Alignment ssp6 and Pdzd2

DIOPT Version :9

• Sequence 1: NP_001286952.1
• Gene: ssp6 / 38694
• FlyBaseID: FBgn0035676
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_038959013.1
• Gene: Pdzd2 / 65034
• RGDID: 619958
• Length: 2818
• Species: Rattus norvegicus
• Alignment Length: 1119
• Identity: 199/1119 - (17%)
• Similarity: 316/1119 - (28%)
• Gaps: 443/1119 - (39%)

  Fly    27 VSISASNATSVGSLIAAACQQEQPHPHQHYSQSQQQHLYHQSHQQASHYVNGTGSLGRLKFHKS- 90
            :.::.:....||..|.|.|...:..|...|..|.                 ..||:.:::.:.|
  Rat   730 MEVTLNKEPRVGLGIGACCLALENSPPGIYIHSL-----------------APGSVAKMESNLSR 777

  Fly    91 ----LDASDEEIEYAQLSRSTH-------------ILGRHKSERYLASNPDEDRRRRTIIVEKKN 138
                |:.:...:.:|.||: .|             ::|||.:.:......||...|.|....::.
  Rat   778 GDQILEVNSVNVRHAALSK-VHAILSKCPPGPVRLVIGRHPNPKVSEQEMDEVIARSTYQESREA 841

  Fly   139 NS---YGFTLQSYGIHYKRD---EELEMITYV---------DYV-------EYGGPAYRAGMREG 181
            ||   .|..|:|..: .|:|   .|.|:..|.         |:|       ::.|..|...  |.
  Rat   842 NSSPGLGTPLKSPSL-AKKDSLLSESELSQYFVHDGQGSLSDFVVAGSEDEDHPGSGYETS--ED 903

  Fly   182 DVILSINGKDMEKADHKTIVEFIKQCDTRMRMVVLFEDCVRKVDLHMRY-IQLQSMLQQKMNELE 245
            ..:|.:  ....||...::|....|..:.:              ||.:. :..|:.|......|.
  Rat   904 GSLLPV--PSAHKARANSLVTLGSQRTSGL--------------LHKQVTVARQASLPGSPQVLR 952

  Fly   246 RVHLRER-------------ELLEGKWKTHSLPARKKANANTSPSDGEGVSPTEVAGEAGFYRPA 297
            ...||:|             |..:|:....|||       ...|..|:.:...:.       |||
  Rat   953 NPLLRQRRVRCYDSNGGSDDEDFDGEGDCISLP-------GVLPGPGKPLVEDDT-------RPA 1003

  Fly   298 LSTE----------------------DVPNIAA---RQHGV-GGPGIIPPPAQFMLTYHYLDPTY 336
            |:|.                      .||.:.:   .:|.: .|.|..||....:
  Rat  1004 LTTSSKSIDVNKQEERLQKPLVSKACSVPLLGSSLDSEHSILNGTGGTPPKVASL---------- 1058

  Fly   337 RYVLRPTHGSS-EEFVDGLGLQRSSSDHQPPAQRYVLQQTESVDANSMTQPT-TTAPTQYHSTTG 399
                 |..|.: :....|.|.:..|.....|...|.:             || |.:|....:.|
  Rat  1059 -----PGSGETPKNGPRGSGRKEMSGSRSSPKLEYRV-------------PTDTQSPRSPENHT- 1104

  Fly   400 GSVKPPAPPPRTCEKHKPPAKPPKPEKEKSSGKHCHVGHSCNPC---------------LGHFRW 449
               .||........:|||.|: ..|..::|..:....|.:..||               .|....
  Rat  1105 ---SPPQKSENLVSRHKPVAR-ISPHYKRSDAEEAPGGTANGPCAQDLKVQASPVKDPVTGRQPG 1165

  Fly   450 KSAEK----SAVPAPDNVSLDAYDLASPCCDTHCVPSRRRHRQHKEHTHKHKHRDRERVESKEQR 510
            .:|||    :..|...:|..:....::||.....:|:                       ...|.
  Rat  1166 GTAEKELQGNPTPGDSSVPTNCGPASTPCHPNTGLPT-----------------------ENPQG 1207

  Fly   511 VRPKSTSHASPNANGGAGSGHHHHHHHHHHSHEQQQQQQQQQQQQQQQQQQQQQQQPI--QTVPH 573
            ..|:...|.     |....|...|......|.|......:.....:|..|.:...||:  :|...
  Rat  1208 AAPECVPHP-----GTGWDGSSEHLCSPGKSREVHPDSSETPTVAEQVHQPESLSQPVSPRTSEP 1267

  Fly   574 HHHYPHQMHNPCQ---------------------VQSQSGSTRSRYFDLASGLASHCSL--HSCT 615
            ......:|..|.|                     ....|.|||.....:::|.|...::  .|..
  Rat  1268 ESQGISKMKPPSQRCVSPREKASTPPDSSRAWAAPGDSSPSTRRIAVPMSTGAAPATAIPQASLV 1332

  Fly   616 SSEFATG--------------------------DTA------SYTTS----ISTD-TLFWDPTS- 642
            |.|.:.|                          |||      |:.:|    ::|: ||...|.:
  Rat  1333 SQERSRGLSGPSKGLGTKELCIPKSLKDGALLEDTAPASGKMSHASSPSGPVATERTLSGSPENP 1397

  Fly   643 ---------ETAQSRQHSTKSR-------QSYEQQPQQQQPTHQGHHHHHHHQGDYHQRYHVTTT 691
                     |.:::|...:..:       .::|.||    |...|....||.|       .|.:.
  Rat  1398 VTDIDNFIEEASEARLSQSPQKADCRAHGDTFESQP----PGGAGSSSSHHAQ-------MVRSD 1451

  Fly   692 QMQPQQIYPNTIAYVQKPKSWDNLANKAGFNVGYGYLDTVAVKPAIKMQIAQQRHSMPRR---NP 753
            |....:....|.:  ..|:.|                   |::|::...|...:|....:   |.
  Rat  1452 QTSSPRKTGGTGS--PPPQQW-------------------ALQPSVLDSIHPDKHLAVNKTFLNN 1495

  Fly   754 YGR-----------------------YSTYGDVE-------------------NYAPP------P 770
            |.|                       .|.||:.|                   |::||      |
  Rat  1496 YSRNFSNFHEDSISLSGPGGSSEPSPSSMYGNAEDSSSDPESLAEDPGAAARNNWSPPLSPESSP 1560

  Fly   771 TEFVGE-----LTTTTT-----TTITAKSTEELLAACDCLTPQQQAAIKA--------------- 810
            .|...|     :...:|     |.:||....: :|.|..|..||:|..|.
  Rat  1561 KEGSSESEDERIEICSTDGCPGTPVTAPPPTQ-VALCPVLPVQQRAVCKPVGDICERACFVPGAS 1624

  Fly   811 ------------------------AQYQLSQNQKLSHQNSCQLGYYSHLPRPTTDVGTSTTSQQV 851
                                    |....|||    |...|..|        ..|| |||:|..
  Rat  1625 RTSIPDSSQPFSFLDVSSEEPETWASINASQN----HMPVCTEG--------IMDV-TSTSSNM- 1675

  Fly   852 HGAGDVQTTSEATR 865
               ||.| :|:.||
  Rat  1676 ---GDSQ-SSQMTR 1685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	21/107 (20%)
Pdzd2	XP_038959013.1	PDZ_signaling	335..416	CDD:238492
		PDZ_signaling	590..671	CDD:238492
		PDZ_signaling	729..813	CDD:238492	16/100 (16%)
		PHA03247	<985..1446	CDD:223021	91/539 (17%)
		PDZ_signaling	2603..2677	CDD:238492
		PDZ_signaling	2731..2813	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900