DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssp6 and grip2a

DIOPT Version :9

Sequence 1:	NP_001286952.1	Gene:	ssp6 / 38694	FlyBaseID:	FBgn0035676	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	XP_017212845.1	Gene:	grip2a / 568084	ZFINID:	ZDB-GENE-081104-132	Length:	1100	Species:	Danio rerio

Alignment Length:	516	Identity:	109/516 - (21%)
Similarity:	183/516 - (35%)	Gaps:	146/516 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 TAASSAATT-----------AAAVSISASNATSVGSLIAAACQQE-QP-----HPHQHYSQSQQQ 62
            ||:.|:..|           ...|.:.....:|:|..|:..|.:| :|     .|....::|.|.
Zfish    67 TASDSSGFTNRCSLADEQRGVTTVELIKKEGSSLGLTISGGCDKEGKPRVSNLRPGGLAARSDQL 131

  Fly    63 HL--YHQSHQQASHYVNGTGSLGRLKFHKSLDASDE-------EIEYAQLSRSTHILGRHKSERY 118
            ::  |.:|       |||. :|.:|:..:.:.....       |:||             :...:
Zfish   132 NVGDYIKS-------VNGI-NLSKLRHDEIISMLKNIGERVVLEVEY-------------ELPPF 175

  Fly   119 LASNP-DEDRRRRTIIVEKKNNSYGFTLQSYGIHYKRDEELEMITYVDYVEYGGPAYRAG-MREG 181
            ..||| ....:...:.:||:.||:||.|:. |.|....:...::  |.||..||||.|.| :|.|
Zfish   176 APSNPCSVISKTIEVCLEKEGNSFGFVLRG-GFHEDWHKARPLV--VTYVRPGGPADREGTLRAG 237

  Fly   182 DVILSINGKDMEKADHKTIVEFIKQCDTRMRMVVLFEDCVRKVDLHMRYIQLQSMLQQKMNELER 246
            |.:||:||..:.:..|...:..|.|.......::.::            |.:...:|:....|:.
Zfish   238 DRVLSVNGVAVNRQKHADALTLIMQSSQEAFFLIEYD------------IMVMDSVQKSSGPLQV 290

  Fly   247 VHLRERELLEGKWKTHSLPARKKANANTSPSDGEGVSPTEVAGEAGFYR--------PALSTEDV 303
            ...|....:.|...:.||...|:....      :.:.|..||...|...        ..:|||..
Zfish   291 DIARSAGSVLGLSLSTSLYRNKQVITI------QKIKPASVADRCGALHAGDILLAIDGMSTEHC 349

  Fly   304 PNIAARQHGVGGPGIIPPPAQFMLTYHYLDPTYRYVLRPTHGSSEEFVDGLGLQRSSSDHQPPAQ 368
            ..:.|:|                |.....:.|...:|...|.|.    |.:.:|||.......::
Zfish   350 SLMEAQQ----------------LLSSSSELTKLEILPSLHSSQ----DTVRVQRSCQRQWDSSE 394

  Fly   369 RYVLQQTESVDANSMTQP--TTTAPTQYHSTTGGSVKPPAPPPRTCEKHKPPAKPPKPEKEKSSG 431
            .|    |.::.|...|..  :.|.||..|.:....|                       ...:||
Zfish   395 NY----TNALPAFQKTPSAWSQTTPTPSHRSVSSGV-----------------------SANTSG 432

  Fly   432 KHCHVGHSCNPCLGHFRWKSAEKSAVPAPDNVSLDAYDLASPCCDTHCVPSRRRHRQHKEH 492
            .|   .::|..       :||..:..|:.   :|.:|. :||    .|..::||||: |||
Zfish   433 FH---SYNCGS-------QSAYPNTYPSS---TLPSYP-SSP----RCSATKRRHRR-KEH 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	28/86 (33%)
grip2a	XP_017212845.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900