DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssp6 and grip2b

DIOPT Version :9

Sequence 1:	NP_001286952.1	Gene:	ssp6 / 38694	FlyBaseID:	FBgn0035676	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	XP_021325304.1	Gene:	grip2b / 562290	ZFINID:	ZDB-GENE-070705-172	Length:	1086	Species:	Danio rerio

Alignment Length:	339	Identity:	71/339 - (20%)
Similarity:	124/339 - (36%)	Gaps:	85/339 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 IIVEKKNNSYGFTLQSYGIHYKRDEELEMITYVDYVEYGGPAYRAG-MREGDVILSINGKDMEKA 195
            |.::|:.||:||.::. |.|....:...::  |.:|..||||.|.| ::.||.|||::|..:..|
Zfish   148 ICLQKEGNSFGFVMRG-GAHEDWHKSRPLV--VTHVRPGGPADREGTLKSGDRILSVDGVVLHSA 209

  Fly   196 DHKTIVEFIKQCDTRMRMVVLFE----DCVRKVD----------------------LHMRYIQLQ 234
            .|...:..:.||.......:.::    |.|....                      ||.   ..|
Zfish   210 THSDALVVLTQCGQEALFQIEYDVSIMDSVTNASGPLLVEIAKAPGASLGVTLTTALHR---NKQ 271

  Fly   235 SMLQQKM---NELER---VHLREREL-LEGKWKTH-SLPARKKANANTSPSDGEGVSP---TEVA 288
            :::..|:   :.::|   :|:.:..| ::|....| ||....:..|:||......:.|   |.:.
Zfish   272 AIVIDKIKPGSVVDRSGALHVGDHILSIDGTSTEHCSLLEATQLLASTSDQTKLEILPAHQTRLP 336

  Fly   289 GEAGFYRPALSTEDVPNIAARQHGVGGPGIIPPPAQFMLTYHYLDP--TYRYVLRPTHGSSEEFV 351
            |:         .:|...:....|.                 |..||  .|.:...|.|..:..:.
Zfish   337 GK---------PQDTVKVQKSDHP-----------------HCWDPCVNYCHSQHPGHCKTSTWT 375

  Fly   352 DGLGLQRSSSDHQPPAQRYVLQQTESVDANSMTQPTTTAPTQYHSTTGGSVKPPAPPPRTCEKHK 416
            .......||.|:           .:||..::.:..:||  |...::.|.|..|.|.||.:.....
Zfish   376 SASSNPSSSQDY-----------CKSVVCSNFSPGSTT--TSGMTSQGSSTLPRAAPPMSPRNSM 427

  Fly   417 PPAKPPKPEKEKSS 430
            ...:..|.|.:.||
Zfish   428 LKRRQRKKEHKSSS 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	26/84 (31%)
grip2b	XP_021325304.1	PDZ_signaling	45..127	CDD:238492
		PDZ	144..232	CDD:214570	26/86 (30%)
		PDZ_signaling	245..328	CDD:238492	14/85 (16%)
		PDZ_signaling	462..548	CDD:238492
		PDZ_signaling	561..643	CDD:238492
		PDZ_signaling	659..740	CDD:238492
		Peptidase_S41	672..>841	CDD:321971
		PDZ_signaling	970..1050	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910