DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssp6 and lnx1

DIOPT Version :9

Sequence 1:	NP_001286952.1	Gene:	ssp6 / 38694	FlyBaseID:	FBgn0035676	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	XP_005160562.1	Gene:	lnx1 / 561226	ZFINID:	ZDB-GENE-030131-9439	Length:	769	Species:	Danio rerio

Alignment Length:	446	Identity:	91/446 - (20%)
Similarity:	130/446 - (29%)	Gaps:	168/446 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 YAQLSRSTHILGRHKSERYLASNPDEDR---RRRTIIVEKKNNSYGFTLQSYGIHYKRDEELE-- 159
            :.:|:|:..:|.|.||...:|::..|:|   |...|..|.:.    |.|.... |...|.|:.
Zfish   241 FRRLNRAFSVLRRTKSGTAVANDTTEERDNLRNANIPAEGEL----FALPQLH-HLIPDGEVTSI 300

  Fly   160 MITYVDYVE------YGG-----------PAYRAG-------MREGDVILSINGKDMEKADHKTI 200
            .||..|..|      .||           ..||.|       :..||:||.:||.|:....|...
Zfish   301 KITRADPCEPLAISIVGGNETPLVRILIQDIYREGVIARDGRLLPGDMILKVNGIDISNVPHCYA 365

  Fly   201 VEFIKQCDTRMRMVVLFED-------------------------------------------CVR 222
            |..:||..|.:|:.||.|.                                           .||
Zfish   366 VAALKQPCTLLRLTVLREQRHRYRSHHHSPTEAFPAHTATIRDDSLHVVLVKRAPDEQLGIKLVR 430

  Fly   223 KVDLHMRYI--QLQSMLQQKMNEL------------------------------ERVHL---RER 252
            :.|.|..:|  .|:..|..:...|                              :|||.   |:.
Zfish   431 RPDEHGVFIFHLLEGGLAARDGRLRVDDRVLAINGHDLRYGAPEHAALLIQASEDRVHFIVSRQT 495

  Fly   253 E------LLEGKWK------------THSL------PA--RKKANANTSPSDGEGVSPTEVAGEA 291
            .      |.|..|.            .|:|      ||  .|.......|.|..|::........
Zfish   496 HIPAPDILQEAPWNMEGPPPYSPVDIEHTLLDSCQKPACYEKTVTLLKEPHDSLGMTVAGGMSSR 560

  Fly   292 GFYRPALSTEDVPNIAARQHGVGGPGIIPPPAQFMLTYHYLDPTYRYVLRPTHGSSEEFVDGLGL 356
            |:..|...|...||....|.|....|.|                    |...:|     ||..|:
Zfish   561 GWDLPVYVTNVDPNGVVGQEGSIRKGDI--------------------LLNVNG-----VDLTGV 600

  Fly   357 QRSSS-----DHQPPAQRYVLQQTESVDANSMTQPTTTAPTQYHSTTGGSVKPPAP 407
            .||.:     :...|....||:.....:::....|...:|.....::.|.||.|.|
Zfish   601 TRSEAVANLKNTSSPVVLQVLEMRPPNESSLDCMPPLHSPCALSPSSPGDVKLPPP 656

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	29/111 (26%)
lnx1	XP_005160562.1	RING	57..93	CDD:214546
		PDZ_signaling	297..381	CDD:238492	22/83 (27%)
		PDZ_signaling	411..491	CDD:238492	11/79 (14%)
		PDZ_signaling	536..621	CDD:238492	21/109 (19%)
		DegQ	<548..621	CDD:223343	18/97 (19%)
		PDZ_signaling	678..762	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900