Protein Alignment ssp6 and grid2ipb

DIOPT Version :9

• Sequence 1: NP_001286952.1
• Gene: ssp6 / 38694
• FlyBaseID: FBgn0035676
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_009304908.1
• Gene: grid2ipb / 559717
• ZFINID: ZDB-GENE-040724-161
• Length: 1383
• Species: Danio rerio
• Alignment Length: 1126
• Identity: 194/1126 - (17%)
• Similarity: 323/1126 - (28%)
• Gaps: 466/1126 - (41%)

  Fly    39 SLIAAACQQE---QPHPHQHYSQSQQQHLYHQSHQQASHYVNGTGSLGRLKFHKSLDASDEEIEY 100
            |||...|:.:   :|......|:||..|...|..::||.....||.                 |.
Zfish   263 SLINRMCRSKSLGEPQNRLRRSRSQDHHERPQGSKRASSVPRDTGD-----------------EP 310

  Fly   101 AQLSRSTHILGRHKSERYLASNPDEDRRRRTIIVEKKNNSYGFTLQSYGIHYKRDEELEMITYVD 165
            ||..|:.     .||...:.:.......:|||.|.:...|:||||:.:.           ..::|
Zfish   311 AQNDRTL-----RKSNTMIPTQYVSGVNQRTIRVYRGKKSFGFTLRGHA-----------PVWID 359

  Fly   166 YVEYGGPAYRAGMREGDVILSINGKDMEKADHKTIVEFIKQCDTRMRMVV--------------- 215
            .|..|.||...|::.||.||.:||.||....|:.:|..::.......:||
Zfish   360 SVMPGSPAEACGLKTGDRILFLNGLDMRNCSHEKVVSMLQGSGAMPSLVVEEGPVDYPQSDSEPE 424

  Fly   216 ------------------LFEDCVRKVDLHMRYI--QLQSML----------------------- 237
                              :.|.....:.:|.|..  ||:.:|
Zfish   425 ETPSAPRSRSPALSSLQWVAEILPPSIRVHGRTFSQQLEHLLTLQERYTICKALETFFQHRNVDT 489

  Fly   238 ---------------------QQKMNELERVHLR------------EREL-LEGKWKTHSLPARK 268
                                 .|.:...|:.|.:            |.|: .|...::.|:....
Zfish   490 LIVDVFPVLDTPAKQLIWQFIYQLLTYEEQEHCKTKIARFLGFKSAEPEVGAETHRRSSSMRVSG 554

  Fly   269 KANANT------------------------SPSD---GEGVS---------PTEVAGEAGFYRPA 297
            .::.||                        :|.:   |:|.|         .|.|..|.|...|.
Zfish   555 TSHKNTVRERSSDDCIIGTHLGMGTFTDPVTPEERQCGDGTSFPESPDLSHMTGVYTELGNVYPV 619

  Fly   298 LSTEDVPNIAA-RQHGVGGPGIIPPPAQFMLTYHYLDPTYRYVLRPTHGSSEEFVDGLGLQRSSS 361
            .|::.:.:.:: |..|:|                 |..:..|....||.::.....||.|..:.|
Zfish   620 KSSQSLQSHSSPRAAGMG-----------------LAESNTYTQSFTHSTAGNRKSGLSLTWTDS 667

  Fly   362 DHQPPAQRYVLQQT----ESVDANSMTQPTTTAPTQYHSTTGGSVKPPAPPPRTCEKHKPPAKP- 421
            ...|..:.|  |||    :|||:|           .|.|..    .|||.|..:.|....|.:.
Zfish   668 FPGPQFETY--QQTVASPDSVDSN-----------PYVSLD----SPPASPLPSDELSPLPQRRK 715

  Fly   422 ----PKPEKEKSSGKHC-----HVGHSCNPCLGHFRW--KSAEKSAVPAPDNVSLDAYDLASPCC 475
                .:|.:.:.:.|..     .:||..| .:..|:.  ...|:.:......|::..::|:|...
Zfish   716 LFTFSRPPRSRDTDKFLDALSEQLGHRVN-IVDDFKGGENDYEEMSFQDEQEVNMLPHELSSASS 779

  Fly   476 DTHCVPSRRRHRQHKEHTHKHKHRDRERVESKEQRVRPKSTSHASPNANGGAGSGH--------- 531
            :.|                                    |:|..|.:.:..:||.|
Zfish   780 EDH------------------------------------SSSDDSTSVSYSSGSDHIPPPPQSPP 808

  Fly   532 -------------------HH--------HHH------------------------------HHH 539
                               .|        .||                              ...
Zfish   809 PPPPPLQFTDSPSPLPITPEHLPQPPPAFQHHPIIAPPPPPPRPFLANRPSLHKVLPTREELRAQ 873

  Fly   540 HSHEQQQQQQQQQQQQQQQQQQQQQQQPI-QTVPHHHHYPHQMHNPCQVQSQSGSTRSRYFDLAS 603
            |||  .::...|...|...|..|.:..|| |:.||..  |...|...|
Zfish   874 HSH--PRRSSPQPSSQPILQLHQPKAHPILQSSPHTS--PQPPHTSAQ----------------- 917

  Fly   604 GLASHCSLHSCTSSEFATGDTASYTTSISTDTLFWDPTSETAQSRQHSTKSRQSYE--------- 659
                |..|...:.|.:.:..|....||          .|.|.|...||..|:||:|
Zfish   918 ----HTRLQHPSQSIYQSQQTTVPRTS----------PSLTKQKSLHSQPSQQSFEGTLSSKVPP 968

  Fly   660 ----------QQPQQQQPTHQGHHHHH------------HHQG----------DYH--------- 683
                      ..|...:|:.:...::|            :.:|          |||
Zfish   969 PPPPPLPPPCDPPPLPKPSPKASDNNHMSVKRLRWEQVENSEGTIWGQLGDDPDYHKLSDMVKYL 1033

  Fly   684 --------QRYHVTTTQ--MQPQQIYPNTIAYVQKPKSWDNLANKAGFNVG-------------- 724
                    ||..::..:  ..|:.:....:..:        |::|..:|..
Zfish  1034 DLDLYFGTQRNSISLPEPTFLPENLKKKDVVEI--------LSHKKAYNASILIAHLKLAPKELR 1090

  Fly   725 --YGYLDTVAVKPAIKMQIAQQRHSMPRRNPYGRYSTYGDVENYAPPPTEFVGEL---------- 777
              ...:.|..::||   .|.|.....|......::..|.........|.:||.::
Zfish  1091 DILMTMSTERLEPA---HIKQLLLYAPDDEEVKQFQHYDQDPAKLSEPDQFVLQMLLVPEYKTRL 1152

  Fly   778 -TTTTTTTITAKSTEELLAACDCLTPQQQAAIKAAQYQLSQNQKLSH--QNSCQLGYYSHLPRPT 839
             :....||:..| |||:.||.:|        |..|..:|..:::|:.  :....:|.|.:..:|.
Zfish  1153 RSLLFKTTVQEK-TEEMRAAYEC--------IYKASLELKNSKRLAKILEFVLAMGNYLNNGQPK 1208

  Fly   840 TDVGTSTTSQQVHGAGDVQTT 860
            |:   .||..:::...::.||
Zfish  1209 TN---KTTGFKINFLTELNTT 1226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	27/118 (23%)
grid2ipb	XP_009304908.1	PDZ_signaling	9..69	CDD:238492
		PDZ_signaling	80..156	CDD:238492
		HN_L-delphilin-R1_like	183..262	CDD:259820
		PDZ_signaling	335..410	CDD:238492	26/85 (31%)
		HN_L-delphilin-R2_like	451..530	CDD:259821	8/78 (10%)
		FH2	995..1360	CDD:280362	42/255 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810