DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssp6 and Patj

DIOPT Version :9

Sequence 1:	NP_001286952.1	Gene:	ssp6 / 38694	FlyBaseID:	FBgn0035676	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	NP_477342.1	Gene:	Patj / 44100	FlyBaseID:	FBgn0067864	Length:	871	Species:	Drosophila melanogaster

Alignment Length:	485	Identity:	106/485 - (21%)
Similarity:	164/485 - (33%)	Gaps:	129/485 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PMSTSCQSIATAASSAATTAAAVSISASNATSVGSLIAAACQQEQPHPHQHYSQSQQQHLYHQSH 69
            ||.|     ..|.:|:|||..:.||:..             .:|:..|......:....:...:.
  Fly   433 PMPT-----PVATTSSATTTPSRSITRE-------------LEEEALPAPEAFMTTPPSVTTMTT 479

  Fly    70 QQASHYVNGTGSLGRLKFHKSLDASDEEI--EYAQLSRSTH-----ILGRHKSERYLASNPDEDR 127
            ...|.:  |.|. ..:....|||.|.:.|  |...|:..|.     ::.|||    ..::|:...
  Fly   480 TTLSSF--GAGK-QLVAVRDSLDGSTKIIPTEVVPLADKTEAKNSGVITRHK----YYTDPELSD 537

  Fly   128 RRRTIIVEKKNNSYG------------FTLQSYGI------HYKRDEELEMITYVDYVEYGGPAY 174
            ...|.|:.|.....|            |.:...||      ..:...|:....|:..:...||..
  Fly   538 DAETEIIRKWQKIVGSDVEVIVAQIKKFAVGGLGISLEGTVDVEGGREVRPHHYIRSILPDGPVG 602

  Fly   175 RAG-MREGDVILSINGKDMEKADHKTIVEFIKQCDTRMRMVVLFEDCVRKVDLHMRYIQLQSMLQ 238
            ..| :|.||.:|.:||:.:...:|..:|..:|:....:|||     |.|.        :..|:|.
  Fly   603 VNGVLRSGDELLEVNGERLLGMNHLEVVAILKELPLDVRMV-----CGRN--------RNSSLLP 654

  Fly   239 QKMNELERVHLRERELLEGKWKTHSLPARKK----ANANTSPSDGEGVSPTEVAGEAGFYR-PAL 298
            ...:.|:::......||..   |..|...|.    |.|. |.:||:.|:    |..|.|.: .:.
  Fly   655 FSDDTLKKLSNNFENLLPA---TDRLVKAKSDGSLATAG-SVADGDSVA----AAAASFSKLKSR 711

  Fly   299 STEDV---------PNIAARQHGVGGPGIIPPPAQFMLTYH-YLDPTYRYVL------------- 340
            |.|.:         |.|.....|..|.|.      .:|.|. .|||....::
  Fly   712 SLEPLTGLAMWSSQPQIIELVKGDRGLGF------SILDYQDPLDPNDTLIVIRSLVPGGVAQLD 770

  Fly   341 -RPTHGSSEEFVDGLGLQRSSSDHQPPAQRYV------------LQQTESVDANSMTQPTTTAPT 392
             |...|....||:.:.|:.:|.|....|.:..            |..|:    ||: :..:.|.|
  Fly   771 GRLIPGDRLLFVNSINLENASLDQAVQALKGASKGVVRIGVAKPLPMTD----NSL-KACSNAST 830

  Fly   393 QYHSTTGGSVKPPAPPPRTCEKHKPPAKPP 422
            ....|......|||.|...     |||.||
  Fly   831 TSEETLDAQPSPPALPTVA-----PPAMPP 855

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	24/104 (23%)
Patj	NP_477342.1	L27	12..70	CDD:295425
		PDZ_signaling	154..226	CDD:238492
		PDZ_signaling	318..400	CDD:238492
		PDZ_signaling	557..643	CDD:238492	18/85 (21%)
		PDZ_signaling	726..807	CDD:238492	18/86 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810