DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ssp6 and CG15803

DIOPT Version :9

Sequence 1:	NP_001286952.1	Gene:	ssp6 / 38694	FlyBaseID:	FBgn0035676	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	NP_001287388.1	Gene:	CG15803 / 42206	FlyBaseID:	FBgn0038606	Length:	880	Species:	Drosophila melanogaster

Alignment Length:	581	Identity:	109/581 - (18%)
Similarity:	176/581 - (30%)	Gaps:	189/581 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SIATAASSAATTAAAVSISASN-------ATSVGSLI-------AAACQQEQPHPHQHYSQSQQQ 62
            |.||||.:||..|||.:.|.|:       ...|.||:       |...:.....|....:..|.|
  Fly   129 SFATAAVAAAAAAAAAAGSGSDGDVGGGGVLDVASLVGLVRGGPAEGTELSAVEPQPSAAVLQLQ 193

  Fly    63 HLYHQSHQQASH---YVNGTGSLGRLKFHKSLDASD-----------EEIEYAQLS--------- 104
            .|...:...|..   .:.|.|.      |..:..|:           :.:.::.||
  Fly   194 QLSELAGDLADFPLPPIPGGGG------HSMVTDSNAGQRPCPRLDLDIVPFSILSPPPRPALQM 252

  Fly   105 -------RSTHILGRH------KSERYLASNPD----------------EDRRRRTIIVEKKNNS 140
                   |......||      .|:|.|.:|.|                :.....|.:||...|.
  Fly   253 LPLETQWRCVQDQNRHIETVIADSKRKLLANEDGGSASASGSGSPDSYMDSPETETYVVELHKNV 317

  Fly   141 YGFTLQSYGIHYKRDEELEMITYVDYVEYGGPAYRAG-MREGDVILSINGKDMEKADHKTIVEFI 204
            ||..:...| :...:|:|..| :|..:..|..|..:| ::..|.|::::|:.:....:...||.:
  Fly   318 YGLGITVAG-YVCEEEDLSGI-FVKSIIEGSAAETSGQIQINDRIVAVDGRSLSGVTNHQAVELL 380

  Fly   205 KQCDTRMRMVVLFEDCVRKVDLHMRYIQLQSMLQQKMNELERVHLRERELLEGKWKTHSLPARKK 269
            :..|     :|                               |||.....|.|:...|...|..:
  Fly   381 RNTD-----IV-------------------------------VHLTLERFLRGRKYEHLQVALTE 409

  Fly   270 ANANTSPS--------DGEGVSPTEVAGEAGF----YRP-------ALSTEDVPNIAARQHGVGG 315
            ....::||        |.:..|...:.|....    :.|       :::||....:.|...|:.|
  Fly   410 IKGTSAPSGLDRSQDKDQDQESQLSMPGSPSIATLSWLPPKSLDADSIATEGDEAVDAEYVGISG 474

  Fly   316 --PGIIPPPAQFML---TYHYLD-------------PTYRYVLRPTHGSSEEFVDGLGLQRSSSD 362
              ...|..|::..:   ..|.||             |....::..|:|.|....|..|.......
  Fly   475 AEDEFIELPSRDTVESNMSHVLDRSDHSGGLTKDQVPRISPIVPLTNGRSLILADDSGNDTDEQC 539

  Fly   363 HQPPAQRYVLQQTESVDANSMTQPTTTAPTQYHSTTGGSVKPPAPPPRTCEKHKPPAKPPKPEKE 427
            .:|        :||:..|...::|.|......     |..|....|    :....|.:.|.|..|
  Fly   540 AEP--------ETETAQARKGSKPETERVKDL-----GDTKTDTDP----DPDLDPGQMPTPTNE 587

  Fly   428 KSSGKHCHVGHSCNPCLGHFR--WKSAEKSAVPAPDNVSLDAYDLASPCCDTHCVPSRRRH 486
            ...       .:.:|.....|  |||.         .:||:.      ..|..|...:|.|
  Fly   588 APV-------KAASPTAASLRVAWKSL---------GISLEG------TVDVECGIEKRPH 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	20/86 (23%)
CG15803	NP_001287388.1	PDZ_signaling	17..89	CDD:238492
		PDZ	307..393	CDD:214570	24/123 (20%)
		PDZ_signaling	605..680	CDD:238492	8/37 (22%)
		PDZ	773..858	CDD:214570
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810