DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssp6 and Mhcl

DIOPT Version :9

Sequence 1:	NP_001286952.1	Gene:	ssp6 / 38694	FlyBaseID:	FBgn0035676	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	NP_732109.2	Gene:	Mhcl / 41955	FlyBaseID:	FBgn0026059	Length:	2194	Species:	Drosophila melanogaster

Alignment Length:	424	Identity:	83/424 - (19%)
Similarity:	141/424 - (33%)	Gaps:	139/424 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 EIEYAQLSRSTHILGRHKSERYL------------ASNPDEDR-----RRRTII---VEKKNNSY 141
            ::|.|:.:||..:..|..:|..|            |.|..|:|     |.|..:   :|:.....
  Fly  1828 QLEDAESARSLAMKARQTAEAELTEVQAMFDESHRARNDAEERANAAHRDRAELQAQIEENEEEL 1892

  Fly   142 GFTLQSYGIHYK--------------------------RDEELEMITYVDYVEYGGPAYRAGMRE 180
            |..::.|....|                          :::..|:...:|.||..|....|.|.:
  Fly  1893 GELMKKYSATVKQLNTEQINVSEAEFKLNEMEAERNNLKEQVAELQHRLDNVENLGDPSMAMMSK 1957

  Fly   181 GDVILSINGKDMEKA----------------DHKTIVEFIKQCDTRMRM-VVLFEDCVRKVDLHM 228
            .   |.:..|::|..                .||..:|.::...|:.:| .:..:|.::|
  Fly  1958 R---LELRTKELESRLELEQATRARLEVQVNRHKEALEKLQNEVTQSKMREMQAQDVIKK----- 2014

  Fly   229 RYIQLQSMLQQKMNELERVHLRERELLEGKWKTHSLPARKKANANTSPSDGEG--------VSPT 285
                .|..|:....|...|..||:|         ||..||.........:.||        ::..
  Fly  2015 ----SQKSLRDMREEFHAVSSREQE---------SLTRRKDLEKKVEQMESEGAALKNDLRLALQ 2066

  Fly   286 EVAGEAGFYRPALSTEDVPNIAARQHGVGGPGIIPPPAQFMLTYHYLDPTYRYVLRPTH--GSSE 348
            .:|.    .:.|:..|....::.....:...|.|.            |...|  |||.|  .||:
  Fly  2067 RIAD----LQQAMEEEGEEELSESDESLSSVGSIS------------DLEDR--LRPVHVKRSSQ 2113

  Fly   349 EFVDG-LGLQRSSSDHQPPAQRYVLQQTESV----DANSMTQPTTTAPTQYHSTTGGSVKPPAPP 408
            :.::| :|....|          |:..|.:|    |.|| .:.|.|:|:..|      :...|..
  Fly  2114 QSLNGSIGGGGGS----------VVSSTRTVVFEKDDNS-PRITVTSPSSPH------IHKLALA 2161

  Fly   409 PRTCEKHKPPAKP---PKPEKEKSSGKHCHVGHS 439
            .:....:||..||   .:.|....:|:  |.||:
  Fly  2162 AKAIPANKPDTKPAASTRMELTVPAGQ--HNGHN 2193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	20/131 (15%)
Mhcl	NP_732109.2	PDZ_signaling	339..426	CDD:238492
		MYSc	556..1317	CDD:214580
		MYSc_Myo18	575..1305	CDD:276837
		GBP_C	<1540..1750	CDD:303769
		COG1340	1565..1833	CDD:224259	1/4 (25%)
		coiled coil	1723..1734	CDD:293879
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900