DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssp6 and pdzk1

DIOPT Version :9

Sequence 1:	NP_001286952.1	Gene:	ssp6 / 38694	FlyBaseID:	FBgn0035676	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	NP_001122142.2	Gene:	pdzk1 / 337325	ZFINID:	ZDB-GENE-031222-1	Length:	553	Species:	Danio rerio

Alignment Length:	314	Identity:	68/314 - (21%)
Similarity:	118/314 - (37%)	Gaps:	94/314 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 QSQQQHLY-HQSHQQASHYV-----NGTGSLGRLK-----------FHKSLDASDEEIEYAQLSR 105
            :||....| ...|.:..|.:     .|...|..||           |..:|    |..:.|.|.|
Zfish    15 ESQGYGFYLRVEHGEEGHLIRALEMGGAAELAGLKDGDRILRVNNTFVDNL----EHTQVADLVR 75

  Fly   106 ST------HILGRHKSERYLASN---------PDEDR-----------RRRTIIVEKKNNSYGFT 144
            ::      |:||....:...|:|         |.:.:           :.:...::|.::.:||:
Zfish    76 NSGMSVTLHVLGEEAYKTAKANNVNLADLQSLPGQSQPTMNGVSTPAAKAKLCYLQKSSSGFGFS 140

  Fly   145 LQS-YGIHYKRDEELEMITYVDYVEYGGPAYRAGMREGDVILSINGKDMEKADHKTIVEFIKQCD 208
            |:| .|.|        .|..||.|. ||.|.:||::.||.::.||.:::|...|..||:.:|...
Zfish   141 LKSTKGAH--------GIFMVDVVS-GGVADQAGVKLGDRLVEINSENVEHLVHDQIVQKVKAAS 196

  Fly   209 TRMRMVVLFEDCVRKVDLHMRYIQLQSMLQQKMNELERVHLRERELL----------------EG 257
            .|:.::::.|:.       .||.:.:: :|..::.....||..:..:                :.
Zfish   197 DRLMLLLVDEEA-------DRYFKSKN-IQPGVSHATVKHLPHKPRIADMIKRADGYGFMLKEDP 253

  Fly   258 KWKTHSLPARKKANANTSPSDGEGVSPTEVAGEAGFYR-PALSTEDVPNIAARQ 310
            |.|.|.:....|.            ||.|.||.....| .|::.||:.|....|
Zfish   254 KRKGHCIGEIDKG------------SPAERAGMKDMDRLAAVNGEDIENCKHEQ 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	26/86 (30%)
pdzk1	NP_001122142.2	PDZ_signaling	6..86	CDD:238492	16/74 (22%)
		PDZ_signaling	126..204	CDD:238492	26/86 (30%)
		PDZ	232..311	CDD:214570	15/76 (20%)
		PDZ_signaling	392..471	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810