DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ssp6 and Cytip

DIOPT Version :9

Sequence 1:	NP_001286952.1	Gene:	ssp6 / 38694	FlyBaseID:	FBgn0035676	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	NP_001012086.1	Gene:	Cytip / 311047	RGDID:	1307990	Length:	359	Species:	Rattus norvegicus

Alignment Length:	250	Identity:	63/250 - (25%)
Similarity:	114/250 - (45%)	Gaps:	22/250 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 QSQQQHLYHQSHQQASHYVNGTGSLGRLKFHKSLDASDEEIEYAQLSRSTHILGRHKSERYLASN 122
            ||...:|.:.:....|.|...||.|          ..::......|:.:...|.|.:.:..||.:
  Rat    10 QSSNGNLEYCADSAYSSYPTLTGPL----------TVEDNRRIQMLADTVATLPRGRKQLALARS 64

  Fly   123 PD----EDRRRRTIIVEKKNN-SYGFTLQSYGIHYKRDEELEMITYVDYVEYGGPAYRAGMREGD 182
            ..    ...:|:.:.|||::| ::||.:|:|.:..:.....|:.|.:..|:...||:.||::.||
  Rat    65 SSLGDFSCSQRKVVTVEKQDNGTFGFEIQTYRLQNQNICSSEVCTMICKVQEDSPAHCAGLQVGD 129

  Fly   183 VILSINGKDMEKADHKTIVEFIKQCDTRMRMVVLFEDCV-RKVDLHMRYIQLQSMLQQKMNELER 246
            :..::||...|...||.:|:.|:.....:.:..|....: |:.:|..:...|:..|::|..||..
  Rat   130 IFANVNGVSTEGFTHKQVVDLIRSSGNLLTIETLNGTMIHRRAELEAKLQTLKQTLKKKWVELRS 194

  Fly   247 VHLRERELLEGKWKTHSLPARKKANANTSPSDGEGVSPTEVAGEAGFYRPALSTE 301
            :||:|:.||.|  ...:.|..:..|.:.|...|..:.|:    .|...||.||:|
  Rat   195 LHLQEQRLLHG--DAANSPNLENMNLDESSLFGNLLGPS----PAFLDRPRLSSE 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	24/86 (28%)
Cytip	NP_001012086.1	PDZ_signaling	76..161	CDD:238492	24/84 (29%)
Cytip	NP_001012086.1	Interaction with CYTH1. /evidence=ECO:0000250	166..188		4/21 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340852
Domainoid	1	1.000	69	1.000	Domainoid score	I9421
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003007
OrthoInspector	1	1.000	-	-		otm45672
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15963
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.800