DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssp6 and Mpdz

DIOPT Version :9

Sequence 1:	NP_001286952.1	Gene:	ssp6 / 38694	FlyBaseID:	FBgn0035676	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	XP_006238402.1	Gene:	Mpdz / 29365	RGDID:	3105	Length:	2068	Species:	Rattus norvegicus

Alignment Length:	330	Identity:	71/330 - (21%)
Similarity:	119/330 - (36%)	Gaps:	65/330 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ASKPMSTSCQSIATAASSAATTAAAVSISASNATSVGSLI-------AAACQQEQPHPHQHYSQS 59
            |:.|:...|::  |...|...|...:||...:.|.:|::|       .|||:..:........:.
  Rat  1616 ATCPIIPGCET--TIEISKGQTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV 1678

  Fly    60 QQQHLYHQSHQQASHYVNGTGSLGRLKFHKSLDASDEEIEYAQLSRSTHILGRHKSERYLASNPD 124
            ....|...:|.:|.:.:..|....||..::      :|..|                       .
  Rat  1679 NGIDLRKATHDEAINVLRQTPQRVRLTLYR------DEAPY-----------------------K 1714

  Fly   125 EDRRRRTIIVE-KKNNSYGFTLQSYGIHYKRDEELEMITYVDYVEYGGPAYRAG-MREGDVILSI 187
            |:....|..|| :|....|..|...|   ||:   :...:|..:..||.|...| :.:||.||.:
  Rat  1715 EEDVCDTFTVELQKRPGKGLGLSIVG---KRN---DTGVFVSDIVKGGIADADGRLMQGDQILMV 1773

  Fly   188 NGKDMEKADHKTIVEFIKQCDTRMRMVVLFEDCVRKVDLH--MRYIQLQSMLQQKMN--ELERVH 248
            ||:|:..|..:.:...:| |.  :..|.|....::....|  .|..|...:.:..::  .|.|..
  Rat  1774 NGEDVRNATQEAVAALLK-CS--LGTVTLEVGRIKAAPFHSERRPSQSSQVSESSLSSFSLPRSG 1835

  Fly   249 LRERELLEGKWKTHSLPAR----KKANANTSPSDGEGVSPTEVAGEAGFYRPALSTEDVPNIAAR 309
            :...|..|...|.::|.:.    :.......|:|..|:|   :||..|     ....|||...|.
  Rat  1836 IHTSESSESSAKKNALASEIQGLRTVEIKKGPADALGLS---IAGGVG-----SPLGDVPIFIAM 1892

  Fly   310 QHGVG 314
            .|..|
  Rat  1893 MHPNG 1897

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	25/87 (29%)
Mpdz	XP_006238402.1	L27_2	6..63	CDD:117611
		PDZ_signaling	140..222	CDD:238492
		PDZ_signaling	256..335	CDD:238492
		PDZ	374..463	CDD:214570
		PDZ_signaling	552..621	CDD:238492
		PDZ_signaling	693..776	CDD:238492
		PDZ_signaling	993..1063	CDD:238492
		PDZ_signaling	1150..1241	CDD:238492
		PDZ	1348..1433	CDD:214570
		PDZ_signaling	1482..1561	CDD:238492
		MPDZ_u10	1563..1624	CDD:293272	2/7 (29%)
		PDZ	1625..1709	CDD:214570	17/91 (19%)
		PDZ_signaling	1721..1801	CDD:238492	26/88 (30%)
		PDZ_signaling	1858..1943	CDD:238492	13/48 (27%)
		PDZ_signaling	1984..2067	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900