DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssp6 and Pdzd3

DIOPT Version :9

Sequence 1:	NP_001286952.1	Gene:	ssp6 / 38694	FlyBaseID:	FBgn0035676	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	NP_573489.2	Gene:	Pdzd3 / 170761	MGIID:	2429554	Length:	498	Species:	Mus musculus

Alignment Length:	246	Identity:	56/246 - (22%)
Similarity:	92/246 - (37%)	Gaps:	91/246 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 LASNPDED------RRRRTIIVEKKNNSYGFTLQSYGIHYKRDEELEMITYVDYVEYGGPAYRAG 177
            ||.:.|:.      |.|..::.:::..::||.||.   |..:.:.:     |..|:.|..|.|.|
Mouse    32 LAEDQDQSDPWNLHRPRFCLLSKEEEKTFGFHLQQ---HLGKADHV-----VCRVDPGTSAQRQG 88

  Fly   178 MREGDVILSINGKDMEKADHKTIVEFIKQCDTRMRMVVLFEDCVRKVDLHMRYIQLQSMLQQKMN 242
            :||||.||::|...:...||..:|.:|:....|:                     |.::|.|.::
Mouse    89 LREGDRILAVNNNIVAHEDHAVVVRYIRASGPRV---------------------LLTVLAQHVH 132

  Fly   243 ELERVHLRERELLEGKWKTHSLPARKKANANTSPSDGEGVSPT---EVAGEAGFYRPALSTEDVP 304
            ::.||       |:|            ::|...|:...||.|.   .|..|.||   ..|.
Mouse   133 DVARV-------LQG------------SDAFLCPTLPSGVRPRLCHVVKDEGGF---GFSV---- 171

  Fly   305 NIAARQHGVGGP-------------GIIPPPAQFM---------LTYHYLD 333
                 .||..||             ..:||.|:.:         |||:.|:
Mouse   172 -----THGSRGPFWLVLSAGGAAERAGVPPGARLLEVNGASVEKLTYNQLN 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	23/85 (27%)
Pdzd3	NP_573489.2	PDZ_signaling	47..127	CDD:238492	25/108 (23%)
		PDZ_signaling	155..232	CDD:238492	17/75 (23%)
		PDZ	260..345	CDD:214570
		PDZ_signaling	407..471	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810