DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssp6 and Lnx1

DIOPT Version :9

Sequence 1:	NP_001286952.1	Gene:	ssp6 / 38694	FlyBaseID:	FBgn0035676	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	NP_001153049.1	Gene:	Lnx1 / 16924	MGIID:	1278335	Length:	728	Species:	Mus musculus

Alignment Length:	164	Identity:	40/164 - (24%)
Similarity:	67/164 - (40%)	Gaps:	17/164 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 SHQQASHYVNGTGSLGRLKFHKSLDASDEEI--EYAQLSRSTHILGRHKSERYLASNPDEDRRRR 130
            |.:.|:|.:..:.....|...:.:..|..:|  |...:|......|  ..||..||.|......:
Mouse   445 SPESAAHLIQASERRVHLVVSRQVRQSSPDIFQEAGWISNGQQSPG--PGERNTASKPAATCHEK 507

  Fly   131 TIIVEK-KNNSYGFTLQSYGIHYKRDEELEMITYVDYVEYGGPAYRAG-MREGDVILSINGKDME 193
            .:.|.| .:.|.|.|:.....|    .|.::..||..||.||...|.| ::.||::|::||.::.
Mouse   508 VVSVWKDPSESLGMTVGGGASH----REWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELT 568

  Fly   194 KADHKTIVEFIKQCDTRMRMVVL-------FEDC 220
            :......|..:|...:.:.:..|       .|||
Mouse   569 EVSRTEAVAILKSAPSSVVLKALEVKEQEAQEDC 602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	22/87 (25%)
Lnx1	NP_001153049.1	mRING-HC-C3HC3D_LNX1	42..83	CDD:319693
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	185..220
		NPXY motif	185..188
		Interaction with MAGEB18. /evidence=ECO:0000250	186..244
		PDZ_signaling	276..360	CDD:238492
		PDZ_signaling	384..464	CDD:238492	4/18 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	481..500		6/20 (30%)
		PDZ_signaling	506..589	CDD:238492	22/86 (26%)
		PDZ_signaling	637..721	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900