Protein Alignment ssp6 and PARD3B

DIOPT Version :9

• Sequence 1: NP_001286952.1
• Gene: ssp6 / 38694
• FlyBaseID: FBgn0035676
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_011508854.1
• Gene: PARD3B / 117583
• HGNCID: 14446
• Length: 1213
• Species: Homo sapiens
• Alignment Length: 876
• Identity: 147/876 - (16%)
• Similarity: 250/876 - (28%)
• Gaps: 345/876 - (39%)

  Fly    76 VNGTGSLGRLKFHKSLDASDEEIEYAQLSRSTH-------ILGR---HKSERYLASNPD------ 124
            |||....||         :.||:  ..:.|||.       ::.|   |...|.|...||
Human   444 VNGRDVTGR---------TQEEL--VAMLRSTKQGETASLVIARQEGHFLPRELKGEPDCCALSL 497

  Fly   125 EDRRRRTI-IVEKKNNSYGFTLQSYGIHYKRDEELEMITYVDYVEYGGPAYRAG-MREGDVILSI 187
            |...:.|. |....:.|.|..:...| :..|:...::..::..:.:||.|::.| :|..|.::::
Human   498 ETSEQLTFEIPLNDSGSAGLGVSLKG-NKSRETGTDLGIFIKSIIHGGAAFKDGRLRMNDQLIAV 561

  Fly   188 NGKD-MEKADHKTIVEFIKQCDTR------MRMVVL--------------------FEDCVRKVD 225
            ||:. :.|::|:.:....:.....      :::|:|                    ||:|...|.
Human   562 NGESLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRRPERPMEDPAECGAFSKPCFENCQNAVT 626

  Fly   226 LHMR------------------------------------------------------------- 229
            ...|
Human   627 TSRRNDNSILHPLGTCSPQDKQKGLLLPNDGWAESEVPPSPTPHSALGLGLEDYSHSSGVDSAVY 691

  Fly   230 ----YIQLQSMLQQKMNELERVHL---RERELLEGKWKTHSLPARKKANANTSPSDGEGVS---- 283
                :|..:|:...:  :.|.::|   :..:|:..:.|.|||..:|    :.|||...|.:
Human   692 FPDQHINFRSVTPAR--QPESINLKASKSMDLVPDESKVHSLAGQK----SESPSKDFGPTLGLK 750

  Fly   284 --------PTEVA----GEAGFYRPALSTEDVPNIAARQHGVGGPGIIPPPAQFMLTYHYLDPTY 336
                    .|.||    .:..|:||            |.|.|.|.|              .:.::
Human   751 KSSSLESLQTAVAEVRKNDLPFHRP------------RPHMVRGRG--------------CNESF 789

  Fly   337 RYVLRPTHGSSEEF-VDGLGLQRSSSDHQPPAQRYVLQQTESVDANSMTQPTTTAPTQYHSTTGG 400
            |..:..::...||. .|||. .:||...|..             .|..:.|...:..:.......
Human   790 RAAIDKSYDGPEEIEADGLS-DKSSHSGQGA-------------LNCESAPQGNSELEDMENKAR 840

  Fly   401 SVKPPAPPPRTCEKHKPPAKPPK-------PE---KEKSSGKHCHVGHSCNPCLGHFRWKSAEKS 455
            .||......:..||.|...|..|       ||   |:|..|.....|            |..|..
Human   841 KVKKTKEKEKKKEKGKLKVKEKKRKEENEDPERKIKKKGFGAMLRFG------------KKKEDK 893

  Fly   456 AVPAPDNVSLDAYDLASPCCDTHCVPSRRRHRQHKEHTHKHKHRDRERVESKEQRVRPKSTSHAS 520
            ...|....:|                   :|...:|...:....:|||:.:|.|.:|.|......
Human   894 GGKAEQKGTL-------------------KHGGLREEELEKMKEERERIGAKHQELREKQARGLL 939

  Fly   521 PNANGGAGSGHHHHHHHHHHSHEQQQQQQQQQQQQQQQQQQQQQQQPIQTVPHHHHYPHQMHNPC 585
            ..|.|..||.:                           .....:..|.....:|...|....|..
Human   940 DYATGAIGSVY---------------------------DMDDDEMDPNYARVNHFREPCTSANVF 977

  Fly   586 QVQS----------QSGSTRSRYFDLASGLASHCS--LHSCTSSEFATGDTASYTTSISTDTLFW 638
            :..|          :.|...|...|...||.:..:  .|....::      :...|..|||.:
Human   978 RSPSPPRAGPFGYPRDGHPLSPERDHLEGLYAKVNKPYHPLVPAD------SGRPTGGSTDRI-- 1034

  Fly   639 DPTSETAQSRQHSTKSRQS----YEQQPQQQQPTH-----------QGHHHHHHHQGDYHQRYHV 688
                  .:.|:...::|:.    ||....:.:|:.           .|:.|:...:|
Human  1035 ------QKLRKEYYQARREGFPLYEDDEGRARPSEYDLLWVPGRGPDGNAHNLRFEG-------- 1085

  Fly   689 TTTQMQPQQIYPNTIAYVQKPKSWDNLANKAGFNVGYGYLDTVAVKPAIKMQIAQQRH------S 747
                |:.|        |...|:.              |..|.|...||....:.::|.      :
Human  1086 ----MERQ--------YASLPRG--------------GPADPVDYLPAAPRGLYKERELPYYPGA 1124

  Fly   748 MPRRNPYGRYSTYGDV--------ENYAPPP 770
            .|...|.|.|....::        ::|.|||
Human  1125 HPMHPPKGSYPRPTELRVADLRYPQHYPPPP 1155

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	17/94 (18%)
PARD3B	XP_011508854.1	DUF3534	<44..151	CDD:288873
		PDZ_signaling	209..296	CDD:238492
		PDZ_signaling	395..475	CDD:238492	10/41 (24%)
		PDZ_signaling	509..597	CDD:238492	15/88 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900