DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssp6 and grip2

DIOPT Version :9

Sequence 1:	NP_001286952.1	Gene:	ssp6 / 38694	FlyBaseID:	FBgn0035676	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	XP_031757025.1	Gene:	grip2 / 100495373	XenbaseID:	XB-GENE-854056	Length:	1115	Species:	Xenopus tropicalis

Alignment Length:	307	Identity:	64/307 - (20%)
Similarity:	94/307 - (30%)	Gaps:	81/307 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 KKNNSYGFTLQSYGIHYKRDEELEMITYVDYVEYGGPAYRAG-MREGDVILSINGKDMEKADHKT 199
            |:.||:||.::. |.|....:...::  |.||..||||.|.| ::..|.:|.::|..:....|..
Frog   194 KEGNSFGFVMRG-GAHEDWHKSRPLV--VTYVRPGGPADREGTLKVSDRLLCVDGISLHNITHTD 255

  Fly   200 IVEFIKQCDTRMRMVVLFEDCVRKVDLHMRYIQLQSMLQQKMNELERVHLRERELLEGKWKTHSL 264
            .:..::||...    .:|:            |:....|...:.......|.|.....|.....||
Frog   256 ALSILRQCSQE----AVFQ------------IEYDVALMDTVTNASGPLLVEIAKTPGSTLGISL 304

  Fly   265 PARKKANANTSPSDGEGVSPTEVAGEAGFYRP--------ALSTED-------------VPNIAA 308
            ......|......|  .|.|..|....|...|        ..|||.             :.|:..
Frog   305 STGTHRNKQVIVID--KVKPASVVDRCGALHPGDHILSIDGTSTEHCTLMEATQLLASIIENVKL 367

  Fly   309 RQHGVGGPGIIP---------PPAQFMLT----YHYLDPTYRYVLRPTHG----------SSEEF 350
            .        |:|         ||....:.    :|..||...|...|..|          |::|:
Frog   368 E--------ILPAHHSRLSLRPPETVKVQKSDHHHCWDPCVNYCHTPHPGHCKTPTWNSTSNQEY 424

  Fly   351 VDGLGLQRSSSDHQPPAQRYVLQQTESVDANSMTQPTTTAPTQYHST 397
            ...|.....||........:..|       ||.|.|.|..|....:|
Frog   425 CKSLVAANFSSSSVAGTPGFSSQ-------NSNTLPRTAHPMSPRTT 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssp6	NP_001286952.1	PDZ_signaling	130..216	CDD:238492	22/80 (28%)
grip2	XP_031757025.1	PDZ_signaling	87..169	CDD:238492
		PDZ_signaling	187..272	CDD:238492	23/96 (24%)
		PDZ_signaling	287..370	CDD:238492	16/92 (17%)
		PDZ_signaling	499..585	CDD:238492
		PDZ_signaling	598..681	CDD:238492
		PDZ_signaling	697..778	CDD:238492
		PDZ_signaling	1007..1084	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910