DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42269 and HXT9

DIOPT Version :9

Sequence 1:	NP_648019.2	Gene:	CG42269 / 38689	FlyBaseID:	FBgn0259164	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_012316.1	Gene:	HXT9 / 853236	SGDID:	S000003755	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	599	Identity:	121/599 - (20%)
Similarity:	201/599 - (33%)	Gaps:	177/599 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 NNCYMYDVNYTDILAQGKVMADPKWPQVKCRHGWSYN-----FTEIP----------YATVA--- 191
            ||....|::.|:..:.....|    |.||..|..|.|     .||.|          |.|||
Yeast     5 NNTSANDLSTTESNSNSVANA----PSVKTEHNDSKNSLNLDATEPPIDLPQKPLSAYTTVAILC 65

  Fly   192 ---------------TEQNWVCDDAALPTYAQ------------------SIFFLGAIVGGLLFG 223
                           |...:|.....:..:.|                  |||.:|..:||::..
Yeast    66 LMIAFGGFIFGWDTGTISGFVNLSDFIRRFGQKNDKGTYYLSKVRMGLIVSIFNIGCAIGGIVLS 130

  Fly   224 WVADRFGRIPALIGTN---MMGLLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVG 285
            .|.|.:||...||...   ::|:|..:.:  ::.::::.|.|...|........:..:|:.| |.
Yeast   131 KVGDIYGRRIGLITVTAIYVVGILIQITS--INKWYQYFIGRIISGLGVGGIAVLSPMLISE-VA 192

  Fly   286 PK------YRTFVANMSIAIFF------------------TGAACLLPWIAYFLADWKLLAIVTS 326
            ||      .:.:....::.||.                  .|......|..:.::..
Yeast   193 PKQIRGTLVQLYQLMCTMGIFLGYCTNYGTKNYHNATQWRVGLGLCFAWTTFMVSGM-------- 249

  Fly   327 APLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQIFTDSCKRMQEQE-- 389
                      ..||||.|:|:..||.::|   .:.|.|.|...|.........|:.|...|.|
Yeast   250 ----------MFVPESPRYLIEVGKDEEA---KRSLSKSNKVSVDDPALLAEYDTIKAGIELEKL 301

  Fly   390 AQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGH--------VRNVG---------SLGLD 437
            |.|..:|.| |....::.:..|:.::|.....|..|.:        .::||         .:|:.
Yeast   302 AGNASWSEL-LSTKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVGLKDSFQTSIIIGVV 365

  Fly   438 IFFTFTLACFTELPADTLLTVILDRFGRR----WLACSSMVLSGVFSLLAT--VVPVGIYSAALA 496
            .||:..:|.:|           ::|||||    |.|.|.:....||:.:..  :.|.|.....:.
Yeast   366 NFFSSFIAVYT-----------IERFGRRTCLLWGAASMLCCFAVFASVGVTKLWPQGSSHQDIT 419

  Fly   497 IMG---------RFFVNISYNIGLQWA-------AEVLPTVVRAQAVAFI----HIMGYVASIIA 541
            ..|         .||:   ::....||       :|..|..|:::.:|..    .:.|::.|...
Yeast   420 SQGAGNCMIVFTMFFI---FSFATTWAGGCYVIVSETFPLRVKSRGMAIATAANWMWGFLISFFT 481

  Fly   542 PFVVYLANISQALPLIILGILGIIGGLLALLLPETLNHVLPQTLSDGEEFGRGQSIWDFPCLAKQ 606
            ||:....|....  .:.||.|......:...:|||....|.:..:...|   |...|      |.
Yeast   482 PFITGAINFYYG--YVFLGCLVFAYFYVFFFVPETKGLTLEEVNTMWLE---GVPAW------KS 535

  Fly   607 VDDDEDEKRNADVE 620
            ......|:|.||.:
Yeast   536 ASWVPPERRTADYD 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	106/529 (20%)
CG42269	NP_648019.2	MFS	206..545	CDD:119392	85/428 (20%)
HXT9	NP_012316.1	Sugar_tr	64..526	CDD:395036	95/502 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000