Protein Alignment CG42269 and TPO2

DIOPT Version :10

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_011654.1
• Gene: TPO2 / 853039
• SGDID: S000003370
• Length: 614
• Species: Saccharomyces cerevisiae
• Alignment Length: 498
• Identity: 106/498 - (21%)
• Similarity: 169/498 - (33%)
• Gaps: 173/498 - (34%)

  Fly   163 VMADPK----WPQ-VKCRHGWSYNFTEIPYATVATEQNWVCDDAALPTYAQ-------------S 209
            |..||:    ||. |:    |||... :....:.......|....|.|..:             |
Yeast   154 VTGDPENPHNWPSWVR----WSYTVL-LSILVICVAYGSACISGGLGTVEKKYHVGMEAAILSCS 213

  Fly   210 IFFLGAIVGGLLFGWVADRFGR---------------IPALIGTNMMGLLAGVGTAFVSNFWEFA 259
            :..:|..:|.|::..|:|.:||               ||..:..|:..|||   ..|:...|..:
Yeast   214 LMVIGFSLGPLIWSPVSDLYGRRVAYFVSMGLYVIFNIPCALAPNLGCLLA---CRFLCGVWSSS 275

  Fly   260 IMRFFVGFAFDNCF-------TMMYILVLEYVGPKYRTFVANMSIAIFFTGAACLLPWIAYFLAD 317
            .: ..||.:..:.|       .:.:.....||||.....| |..|:: .||...|:.|:....|.
Yeast   276 GL-CLVGGSIADMFPSETRGKAIAFFAFAPYVGPVVGPLV-NGFISV-STGRMDLIFWVNMAFAG 337

  Fly   318 WKLLAIVTSAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQIFTDSC 382
              ::.|::||           :||:...::.:.|..:    |:| |.||.
Yeast   338 --VMWIISSA-----------IPETYAPVILKRKAAR----LRK-ETGNP--------------- 369

  Fly   383 KRMQEQEAQNGKYSVLDLFKSPRLRR-----TTLLLIVIWMAISLVFDGHVRNVGSLGLDIFFTF 442
            |.|.|||||.  .|:.::.::..||.     |..:|:.....:.|::        ||....||.|
Yeast   370 KIMTEQEAQG--VSMSEMMRACLLRPLYFAVTEPVLVATCFYVCLIY--------SLLYAFFFAF 424

  Fly   443 TLACFTEL-------------------------------------------PADTLLTVILDRFG 464
            .: .|.||                                           |.|.||..   :.|
Yeast   425 PV-IFGELYGYKDNLVGLMFIPIVIGALWALATTFYCENKYLQIVKQRKPTPEDRLLGA---KIG 485

  Fly   465 RRWLACSSMVLSGVFSLLATVVPVGIYSAALAIMGRFFVNISYNIG-------LQWAAEVLPTVV 522
            ..:.|.:..:|..  :....::.||..||.|| .|...|.|.|::.       :|:|:..|.|.|
Yeast   486 APFAAIALWILGA--TAYKHIIWVGPASAGLA-FGFGMVLIYYSLNNYIIDCYVQYASSALATKV 547

  Fly   523 RAQAVAFIHIMGYVASIIAPFVVY-----------LANISQAL 554
                  |:...|..|..:....:|           ||.||.|:
Yeast   548 ------FLRSAGGAAFPLFTIQMYHKLNLHWGSWLLAFISTAM 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	104/494 (21%)
TPO2	NP_011654.1	MFS_Tpo1_MDR_like	173..599	CDD:340881	97/475 (20%)