DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42269 and OCT2

DIOPT Version :9

Sequence 1:	NP_648019.2	Gene:	CG42269 / 38689	FlyBaseID:	FBgn0259164	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_178054.1	Gene:	OCT2 / 844274	AraportID:	AT1G79360	Length:	527	Species:	Arabidopsis thaliana

Alignment Length:	598	Identity:	143/598 - (23%)
Similarity:	247/598 - (41%)	Gaps:	127/598 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 NGSDSLPPSMDFDDILPLIGEFGRYQKLLFICMIPFS-FFVAFVYFSQIFLTLIPEQHW------ 118
            :.:.|.|.|:| |.|...||.|| :.:.|...::.|| .|.|...|..:|....|..|.
plant    11 DSNSSSPRSLD-DTIESYIGSFG-WAQFLQAALVSFSGVFDAQQTFISVFTDSEPTWHCTDSNSI 73

  Fly   119 CHVPELDGLDVEARLALSIPMTNGEYNNCYMYDVNYTDILAQGKVMADPKWPQVKCRHGWSYNFT 183
            ||.              ||.      |.|.:                 ||       ..||::::
plant    74 CHE--------------SIS------NICIL-----------------PK-------TAWSWDYS 94

  Fly   184 EIPYATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVAD-RFGRIPALIGTNMMGLLAGV 247
              |:.:|.:|....|..:.:....:|.||:|.::|||:...:|| ..||...|..:.::..::.:
plant    95 --PHVSVISEWGLQCAGSFVKGLPESSFFVGCLIGGLVLSTLADSSLGRKNMLFLSCLVMAISTM 157

  Fly   248 GTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTGAACLLPWIA 312
            .|.|..|.|.:|::||..||......|...:|..|.||.|:|..|..||...|..|... ||.:|
plant   158 LTVFSPNIWVYAVLRFVNGFGRATIGTCALVLSTELVGKKWRGRVGIMSFFGFMLGFLS-LPLMA 221

  Fly   313 YFL--ADWKLLAIVTSAP-LLLAIFTPFVVPESARWLVSQGKVDKAVGILKKL------EKGNG- 367
            |..  :.|::|...||.| ::..:...|.|.||.|||..:|:.::|:.|||::      :..:|
plant   222 YMNRGSSWRILYAWTSIPTIIYCVLVRFFVCESPRWLFVRGRREEAISILKRVASIPSTDVSSGG 286

  Fly   368 --------------RQVPPQTYQIFTDSCKRMQEQEAQNGKYSVLDLFKSPRLRRTTLLLIVIWM 418
                          .:.|.....|||.....::::.|               |:|.:.::.:.:
plant   287 AISMSFSSLPFEEDEEKPSTNVNIFTTMKVLVEKRWA---------------LKRLSAVMAIAF- 335

  Fly   419 AISLVFDGHVRNVGSLGLDIFFTFTLACFTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLA 483
            .|.||:.|....:.:|..:|:.:.......:|||:.:...::|:..||........|.||.|:|.
plant   336 GIGLVYYGMPLALSNLDFNIYLSAAFNALMDLPANLITLFLVDKLSRRNALIGFTALGGVSSVLI 400

  Fly   484 TV---VPVGIYSA---ALAIMGRFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAP 542
            ..   :.:|.:.|   ||.::..|....::|:.:.:..|:.||.||..|:|.......:..:.:|
plant   401 FALHNMRIGNHGALQLALELISYFSACSAFNMEMIYTIELFPTCVRNSAIAMARQALVLGGVFSP 465

  Fly   543 FVVYLANISQALPLIILGI-LGIIGGLLALLLPETLNHVLPQTLSDGEEFGRGQSIWDFPCLAKQ 606
            .:|.....:......:.|: :|:: ||.|:.||||                ||..:.|      .
plant   466 IMVAAGRKNAFWSFGLFGLAIGLL-GLFAVGLPET----------------RGSDLCD------T 507

  Fly   607 VDDDEDEKRNADV 619
            :|::|.:.|.:.|
plant   508 MDEEECKDRRSKV 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	120/509 (24%)
CG42269	NP_648019.2	MFS	206..545	CDD:119392	93/369 (25%)
OCT2	NP_178054.1	MFS_OCT_plant	79..497	CDD:340936	109/467 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.020