Protein Alignment CG42269 and Sv2b

DIOPT Version :9

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_001103223.1
• Gene: Sv2b / 64176
• MGIID: 1927338
• Length: 683
• Species: Mus musculus
• Alignment Length: 622
• Identity: 128/622 - (20%)
• Similarity: 204/622 - (32%)
• Gaps: 253/622 - (40%)

  Fly   173 KCRHG---WSYNFT-------------EIPYATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLL 221
            :|.||   |:..|.             .:.:|..:.|:: :|..::.......|.:||.:.|..:
Mouse   101 ECGHGRFQWTLFFVLGLALMADGVEIFVVSFALPSAEKD-MCLSSSKKGMLGLIVYLGMMAGAFI 164

  Fly   222 FGWVADRFGRIPAL-----IGTNMMGLLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVL 281
            .|.:||:.||...|     |..:...|     ::||..:..|...|...|........:::....
Mouse   165 LGGLADKLGRKKVLSMSLAINASFASL-----SSFVQGYGAFLFCRLISGIGIGGSLPIVFAYFS 224

  Fly   282 EYVGPKYRTFVANMS-IAIFF-TGA--ACLLPW-------------IAYFLADWKLLAIVTSAPL 329
            |::..:.|.  .::| :.||: ||.  |..:.|             ..|....|::..||.:.|.
Mouse   225 EFLSREKRG--EHLSWLGIFWMTGGIYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPA 287

  Fly   330 LLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGR-QVPPQTYQIFTDS----CKRMQE-- 387
            .:::.....:|||.|:|:..||.|:|..|||::...|.| :..|:  ::||.|    .|:|.|
Mouse   288 TVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPE--KVFTVSHIKTPKQMDEFI 350

  Fly   388 ----------------------QEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDG---- 426
                                  |...|..|.|:..:     |..||:|.|:|..::|.:.|
Mouse   351 EIQSSTGTWYQRWLVRFMTIFKQVWDNALYCVMGPY-----RMNTLILAVVWFTMALSYYGLTVW 410

  Fly   427 -----------------------HVRNV-------------GSLGLDIFF-----------TFTL 444
                                   ||...             |.|..|.|.           ||..
Mouse   411 FPDMIRYFQDEEYKSKMKVFFGEHVHGATINFTMENQIHQHGKLVNDKFIKMYFKHVLFEDTFFD 475

  Fly   445 ACFTE------------------------------------------------------------ 449
            .|:.|
Mouse   476 KCYFEDVTSTDTYFKNCTIESTTFYNTDLYKHKFINCRFINSTFLEQKEGCHMDFEEDNDFLIYL 540

  Fly   450 ---------LPADTLLTVILDRFGRRWLACSSMVLSGV--FSLLATVVPVGIYSAALAIMGRFFV 503
                     ||.:.:..:::||.||..:...||::|.|  |.|                   ||.
Mouse   541 VSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCFFL-------------------FFG 586

  Fly   504 NI-SYNIGLQ----------WAA------EVLPTVVRAQAVAFIH-------IMGYVASIIAPFV 544
            |. |..||.|          |.|      |:.||..||.|...::       |:|  .:|.|.||
Mouse   587 NSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILG--NTIFASFV 649

  Fly   545 VYLANISQALPLIILGILGIIGGLLALLLPETLNHVL 581
                .|::.:|:::.....:.|||:||.||||...||
Mouse   650 ----GITKVVPILLAAASLVGGGLIALRLPETREQVL 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	116/591 (20%)
		MFS	206..545	CDD:119392	106/535 (20%)
Sv2b	NP_001103223.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..73
		synapt_SV2	8..683	CDD:130366	128/622 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910