Protein Alignment CG42269 and Slc22a17

DIOPT Version :10

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_001347335.2
• Gene: Slc22a17 / 59049
• MGIID: 1926225
• Length: 627
• Species: Mus musculus
• Alignment Length: 636
• Identity: 175/636 - (27%)
• Similarity: 269/636 - (42%)
• Gaps: 89/636 - (13%)

  Fly    21 PQGGGGGGADALHRRKSGGGN-----------KELQLDMGGFKKGQ-EMAGGNGSDSLPPS-MDF 72
            |.||||...|:......|...           ::||.:....::|: :..|.:.|.:.||. :.|
Mouse    12 PNGGGGNKIDSAVEIAPGSNGQVGSLGDAVPPEQLQGERERRREGEGDALGSSLSLAAPPGPLSF 76

  Fly    73 DDILPLIGEFGRYQKL-LFICMIPFSFFVAFVYFSQIFLTLIPEQHWCHV-------------PE 123
            :.:|..:|..|..|:| |.:|.:|. .|||....|....||.|..| ||.             |.
Mouse    77 EALLAQVGALGGGQQLQLGLCCLPV-LFVALGMASDPIFTLAPPLH-CHYGALPPNASGWEQPPN 139

  Fly   124 LDGLDVEARLALSIPMTNGEYNNCYMYDVNYTDILAQGKVMADPKWPQVKCRHGWSYNFTEIPYA 188
            ..|:.| |..||:....:|.        |..||....|  .|.|.:..  |...|.||  .:|..
Mouse   140 SSGVSV-AGAALAASAASGV--------VTSTDPSCSG--FAPPDFNH--CLKDWDYN--GLPVL 189

  Fly   189 TVATEQNW--VCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPALIGTNMMGLL--AGVGT 249
            |......|  |||........|.:|.||...|.|..|:.||||||...::.|  :||:  .|||.
Mouse   190 TTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLT--LGLVGPCGVGG 252

  Fly   250 AFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTGAACLLPWIAYF 314
            |...:......:||.:||........:|::.||...|..|..|| ::..:...|...|...:|..
Mouse   253 AAAGSSTGIMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA-LAGELVGVGGHFLFLGLALV 316

  Fly   315 LADWKLLAIVTSAPLLLAIF--TPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQI 377
            ..||:.|..:.:||.:|.:|  .|.:..||||||:.:.::::|..:|:.|.:.|    .|....:
Mouse   317 SKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERN----RPHGQML 377

  Fly   378 FTDSCKRMQEQE-----AQNGKYSVLDLFKSPRLRRTTLLL---IVIWMAISLVFDGHVRNVGSL 434
            ..::.:.:||.|     .....:|...|.....:.:..|:|   ..|..||...:    :.||..
Mouse   378 GEEAQEALQELENTCPLPATSTFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCY----QPVGGG 438

  Fly   435 G--LDIFFTFTLACFTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLATVVPVGIY----SA 493
            |  .|.:....||..|...|...|.|.:||||||.:...||.|:|:    |::|.:|::    .|
Mouse   439 GSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGI----ASLVLLGLWDYLNDA 499

  Fly   494 AL---AIMGRFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQALP 555
            |:   :::|.|....|..:....|:||:||.||.:.:..|..:|.:..:..|...........|.
Mouse   500 AITTFSVLGLFSSQASAILSTLLASEVIPTTVRGRGLGLIMALGALGGLSCPAQRLHMGHGAFLQ 564

  Fly   556 LIILGILGIIGGLLALLLPETLNHVLPQTLSDGEEFGRGQSIWDFPCLAKQ 606
            .::|....::..|..:|||||...:||:.|.|||...|       |.|.:|
Mouse   565 HVVLAACALLCILSIMLLPETKRKLLPEVLRDGELCRR-------PSLLRQ 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	141/508 (28%)
Slc22a17	NP_001347335.2	MFS_SLC22A17	170..583	CDD:341003	117/431 (27%)