Protein Alignment CG42269 and sv2a

DIOPT Version :10

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: XP_696434.2
• Gene: sv2a / 568033
• ZFINID: ZDB-GENE-131001-1
• Length: 733
• Species: Danio rerio
• Alignment Length: 601
• Identity: 119/601 - (19%)
• Similarity: 198/601 - (32%)
• Gaps: 210/601 - (34%)

  Fly   173 KCRHG---WSYNFTEIPYATVATEQNWVCDDAALPTYAQS-------------IFFLGAIVGGLL 221
            :|.||   |:..|. :..|.:|...........||:..:.             |.:||.:||..:
Zfish   150 ECGHGRFQWTLYFV-LGLALMADGVEIFVVGFVLPSAEKDMCLSEPNKGMLGLIVYLGMMVGAFV 213

  Fly   222 FGWVADRFGRIPALIGTNMMGLLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGP 286
            :|.:|||.||...|:.:..:..:....::||..:..|...|...|........:::....|::..
Zfish   214 WGGLADRIGRRQTLLISLSINSVFAFFSSFVQGYSSFLFCRLLSGVGIGGSIPIVFSYYSEFLAQ 278

  Fly   287 KYR---------------TFVANMSIAI-------FFTGAACLLPWIAYFLADWKLLAIVTSAPL 329
            :.|               .:.|.|:.||       |..|:       ||....|::..:|.:.|.
Zfish   279 EKRGEHLSWLCMFWMIGGIYAAAMAWAIIPHYGWSFQMGS-------AYQFHSWRVFVLVCAFPS 336

  Fly   330 LLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQ--VPPQTYQIFT-DSCKRMQE---- 387
            :.||.....:|||.|:.:..||.|:|..|||::...|.|.  .|.:.:.:.| .:.|:|.|
Zfish   337 VAAIAALTTMPESPRFYLENGKHDEAWMILKQVHDTNMRAKGYPERVFSVTTIKTVKQMDELVDM 401

  Fly   388 -QEA----QNGKYSVLDLFK----------SPRLRRTTLLLIVIWMAISLVFDG----------- 426
             .||    |..:..:.:||.          :|..||.|.:::.:|.::|..:.|
Zfish   402 GGEATAWHQRWRIKLTNLFHQVWGNFLTVFNPEYRRITYMMMAVWFSMSFSYYGLTVWFPDMIKY 466

  Fly   427 -------------------HV-------------------------------------------- 428
                               ||
Zfish   467 LQKQEYSSRTKVFIKEKVEHVTFNFTLENQIHRNGEYFNNKFLNLKMKSMVFEDSLFEECYFEDI 531

  Fly   429 -------RNVGSLG-------------------------------LD---------IFFTFTLAC 446
                   ||...:.                               ||         |:|...|..
Zfish   532 TSSNTFFRNCTFISTLFYNTDLFKYRLINSKLINSTFLHNKEGCMLDFSDENNAYMIYFVSFLGT 596

  Fly   447 FTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLATVVPVGIYSAALAIMGRFFVNISYNIGL 511
            ...||.:.:..:::|:.||..:...|.|:|.|....   :..|...:|:..:...|..||.   .
Zfish   597 LAVLPGNIVSALLMDKIGRLRMLAGSSVISCVSCFF---LSFGNSESAMIALLCLFGGISI---A 655

  Fly   512 QWAA------EVLPTVVRAQAVAFIHIMGYVA-----SIIAPFVVYLANISQALPLIILGILGII 565
            .|.|      |:.|:..|..|..|::.:..:|     ||...||    .|::|:|::........
Zfish   656 SWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFQSFV----GITKAVPILFASGALAA 716

  Fly   566 GGLLALLLPETLNHVL 581
            |..|||.||||...||
Zfish   717 GSFLALKLPETRGQVL 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	107/570 (19%)
sv2a	XP_696434.2	synapt_SV2	1..733	CDD:130366	119/601 (20%)