Protein Alignment CG42269 and sv2ca

DIOPT Version :9

• Sequence 1: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_001121811.1
• Gene: sv2ca / 562345
• ZFINID: ZDB-GENE-060526-233
• Length: 745
• Species: Danio rerio
• Alignment Length: 679
• Identity: 133/679 - (19%)
• Similarity: 232/679 - (34%)
• Gaps: 248/679 - (36%)

  Fly   123 ELDGL--DVEAR---LALSIPMTNG-----EYNNCYMYDVNYTDILAQGKVMADPKWPQVKCRHG 177
            |..|:  |.:||   :||..|:::|     |..|....|..  ::..|.:::..      :|.||
Zfish    94 EYQGIPSDAKARDGQVALGQPLSDGLKDRRELENERQADEE--ELAQQYELIIQ------ECGHG 150

  Fly   178 ---WSYNFT-------------EIPYATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVA 226
               |...||             .:.:...:.|.:....|:: ..:..||.:||.:||...:|.:|
Zfish   151 RFQWQLFFTLGLALMSDGVEVFVVGFVLPSAETDMCVPDSS-SGWLGSIVYLGMMVGAFFWGGMA 214

  Fly   227 DRFGRIPA-LIGTNMMGLLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYR- 289
            |:.||... ||..::.|..|.: ::||..:..|.:.|...||.......:::....|.:..:.|
Zfish   215 DKVGRRQCLLICMSLNGFFAFL-SSFVQGYGLFLLCRMIAGFGIGGAVPIVFSYFAEVLAREKRG 278

  Fly   290 --------------TFVANMSIAIF------------FTGAACLLPW-----IAYFLADWKLLAI 323
                          .:.:.|:.||.            |........|     .||....|::..:
Zfish   279 EHLSWLCMFWMIGEIYASAMAWAIIPHYGQITTASSQFINYHHYTSWSFSMGSAYQFHSWRVFVV 343

  Fly   324 VTSAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQIFT--------- 379
            |.:.|.:.|:.....:|||.|:.:..||.|:|..|||::...|.| ...|..::||
Zfish   344 VCALPCVCAVVALTFMPESPRFYLEVGKHDEAWMILKQIHDTNMR-ARGQPEKVFTVNRIKIPKQ 407

  Fly   380 -DSCKRMQEQEAQNGKY-----------------SVLDLFKSPRLRRTTLLLIVIWMAISLVFDG 426
             |....|.|    :|.:                 :.|..|..| ::.:|:.|.::|:.:|..:.|
Zfish   408 IDEFVEMHE----SGNFFSKAIFRIKTELHGIWLNFLKCFNYP-VKESTVKLAIVWLTLSFGYYG 467

  Fly   427 ----------HVRN--VGSLGL--------DIFFTFTL--------------------------- 444
                      |::|  ..|.|.        |..|.|||
Zfish   468 LSVWFPDVIKHLQNDEYASKGQRHNNERIEDFTFNFTLENQIHTNSLFINDRFINMKFKSVTFIN 532

  Fly   445 ----ACFTE-------------------------------------------------------- 449
                :||.|
Zfish   533 STFQSCFFEDVTSVGSFFRNCTFIEAVFYNTDIDDSKLKNTDVINSTFYHNKTGCQMTFEDDYSA 597

  Fly   450 --------------LPADTLLTVILDRFGRRWLACSSMVLSGV---FSLLATVVPVGIYSAALAI 497
                          ||.:.:..:::|:.||..:...||:|||:   |....|...:.|....|
Zfish   598 YWVYFVNFLGTLAVLPGNIVSALLMDKIGRLSMLGFSMILSGISCFFLWFGTSESMMIGMLCL-- 660

  Fly   498 MGRFFVNISYNIGLQWAA---------EVLPTVVRAQAVAFIHIMGYVASIIAPFVV-YLANISQ 552
                     || ||..:|         |:.||..|.....|.:.:..:|:::...:. .|..|::
Zfish   661 ---------YN-GLSISAWNSLDVVTTELYPTDRRGTGFGFCNALCKLAAVMGNLIFGSLVGITK 715

  Fly   553 ALPLIILGILGIIGGLLALLLPETLNHVL 581
            |:|:::...:.:.|||:.|.||:|.::||
Zfish   716 AIPILLASSVLVGGGLVGLRLPDTRSNVL 744

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	122/648 (19%)
		MFS	206..545	CDD:119392	99/531 (19%)
sv2ca	NP_001121811.1	synapt_SV2	3..745	CDD:130366	133/679 (20%)
		Spt5_N	73..>141	CDD:288770	13/48 (27%)
		MFS	157..>360	CDD:119392	38/204 (19%)
		MFS	588..>711	CDD:119392	25/134 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910